Results 91 to 100 of about 955,790 (330)

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Deciphering the mechanisms of long non-coding RNAs in ferroptosis: insights into its clinical significance in cancer progression and immunology

Cell Death Discovery
A new type of nonapoptotic, iron-dependent cell death induced by lipid peroxidation is known as ferroptosis. Numerous pathological processes, including inflammation and cancer, have been demonstrated to be influenced by changes in the ferroptosis ...
Shengming Ou, Xiaoya Nie, Xiangyu Qiu, Xin Jin, Geyan Wu, Rongxin Zhang, Jinrong Zhu   +6 more
doaj   +1 more source

A Pilot Double-Blinded, Randomized, Clinical Trial of Topical Virgin Olive Oil Versus Piroxicam Gel in Osteoarthritis of the Knee [PDF]

Osteoarthritis (OA) is the most common type of arthritis, and the knee is the most common site of symptomatic OA.1 Knee OA is responsible for a higher incidence of disability than any other long-term conditions.2 Topical therapies present a therapeutic ...
بقایی, زهرا, بهلولی, شهاب, جستان, مارینا, محمدی, پرهام سعداله, نخستین روحی, بابک   +4 more
core   +1 more source

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian, Peter Auguste, Amy Grove, Anna Brown, Janette Parr, Mubarak Patel, Furqan Butt, Jeremiah Donoghue, Mehdi Yousefi, Jo Parsons   +9 more
wiley   +1 more source

Topical Analgesics

Brazilian Journal of Anesthesiology, 2012
Pain treatment involves the usage of common and opioid analgesics, nonsteroidal anti-inflammatory drugs (NSAIDs) and adjuvant analgesics. Traditionally, these drugs are administered systemically or into the neuraxis. However, when analgesics are applied through these pathways, they are associated with significant side effects, which can hinder its use.
Flores, Murilo Pereira, de Castro, Anita Perpetua Carvalho Rocha, Nascimento, Jedson dos Santos   +2 more
openaire   +2 more sources

Summary Talk at the 3rd KEK Topical Conference on CP Violation

, 1994
A summary of the contributions to this topical conference is presented. The topics discussed ranged from detailing what we know about CP violation, to what we hope to learn in the future, to still unsolved mysteries in the subject.Comment: 12 pages, UCLA/
't Hooft, Adler, Altarelli, Baluni, Barr, Barr, Bell, Bigi, Bochkarev, Cabibbo, Callan, Crewther, Cronin, Dine, Farrar, Flynn, Gilman, Grinstein, Gronau, Gronau, Gronau, Guberina, Hikasa, Hikasa, Isgur, Jackiw, Jarlskog, Kobayashi, Kobzarev, Kuzmin, Kuzmin, London, Manohar, Martinelli, Mori, Nelson, Neubert, Nir, Peccei, Peccei, Peccei, Peccei, R.D. Peccei, Sakharov, Samuel, Shabalin, Steigman, Winstein, Wolfenstein   +48 more
core   +2 more sources

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Enhanced Ocular Bioavailability and Prolonged Duration via Hydrophilic Surface Nanocomposite Vesicles for Topical Drug Administration

Pharmaceutics
Background: Internal ocular diseases, such as macular edema, uveitis, and diabetic macular edema require precise delivery of therapeutic agents to specific regions within the eye. However, the eye’s complex anatomical structure and physiological barriers
Sa Huang, Yuan Xu, Yingyao Luo, Zhijiong Wang, Fan Li, Zhenmiao Qin, Junfeng Ban   +6 more
doaj   +1 more source

Topic Doubling

Nordic Atlas of Language Structures Journal, 2017
Just like the vast majority of the Germanic languages, the Scandinavian languages are verb second (V2) languages where the finite verb occupies the second position in declarative clauses allowing just one constituent to precede it.
openaire   +2 more sources

Fluctuation - induced forces in critical fluids

, 1999
The current knowledge about fluctuation - induced long - ranged forces is summarized. Reference is made in particular to fluids near critical points, for which some new insight has been obtained recently.
Adjari A, Allen S, Allen S, Barber M N, Binder K, Brankov J G, Brankov J G, Bruce A D, Cardy J L, Casimir H B G, Casimir H B G, Chen X S, Danchev D, Danchev D M, Diehl H W, Diehl H W, Dietrich S, Dolan B P, Dzyaloshinskii L E, Elizalde E, Elizalde E, Elizalde E, Esser A, Fisher M E, Freire F, Garcia R, Israelachvili J N, Itzykson C, Kakazu K, Kardar M, Kirsten K, Krech M, Krech M, Law B M, Leseduarte S, Lifshitz E M, M Krech, Milonni P W, Mostepanenko V M, Mostepanenko V M, Musevic I, Privman V, Privman V, Schlesener F, Schwinger J, Spruch L, Svaiter N F, Vilfan M, Ziherl P   +48 more
core   +2 more sources