Results 281 to 290 of about 642,884 (313)

Baricitinib in patients with moderate‐to‐severe atopic dermatitis and inadequate response to topical corticosteroids: results from two randomized monotherapy phase III trials

British Journal of Dermatology, 2020
Baricitinib, an oral selective Janus kinase 1 and 2 inhibitor, effectively reduced atopic dermatitis (AD) severity in a phase II study with concomitant topical corticosteroids.
E. Simpson, J. Lacour, L. Spelman, R. Galimberti, L. Eichenfield, R. Bissonnette, B. King, J. Thyssen, J. Silverberg, T. Bieber, K. Kabashima, Y. Tsunemi, A. Costanzo, E. Guttman‐Yassky, L. Beck, J. Janes, A. DeLozier, M. Gamalo, D. Brinker, T. Cardillo, F. Nunes, A. Paller, A. Wollenberg, K. Reich   +23 more
semanticscholar   +1 more source

SLN and NLC for topical, dermal, and transdermal drug delivery

Expert Opinion on Drug Delivery, 2020
Introduction From a biopharmaceutical standpoint, the skin is recognized as an interesting route for drug delivery. In general, small molecules are able to penetrate the stratum corneum, the outermost layer of the skin.
E. Souto, Iara Baldim, W. P. Oliveira, R. Rao, N. Yadav, F. M. Gama, S. Mahant   +6 more
semanticscholar   +1 more source

Cutaneous candidiasis – an evidence‐based review of topical and systemic treatments to inform clinical practice

Journal of the European Academy of Dermatology and Venereology, 2019
Cutaneous candidiasis is a common skin disease, and several treatments have been investigated within the last fifty years. Yet, systematic reviews are lacking, and evidence‐based topical and systemic treatment strategies remain unclear.
E. Taudorf, G. Jemec, R. Hay, D. Saunte
semanticscholar   +1 more source

Topical ketoconazole: a systematic review of current dermatological applications and future developments

Journal of dermatological treatment (Print), 2019
Introduction: Although labeling changes and market withdrawal have been implemented for oral ketoconazole (KTZ) due to serious adverse effects (AEs), topical KTZ is generally thought to be effective and safe for the treatment of superficial fungal ...
Franchesca Choi, M. Juhász, N. Atanaskova Mesinkovska   +2 more
semanticscholar   +1 more source

Intravenous Versus Topical Tranexamic Acid in Total Knee Arthroplasty: Both Effective in a Randomized Clinical Trial of 640 Patients

Journal of Bone and Joint Surgery. American volume, 2018
Background: Tranexamic acid (TXA) reduces bleeding and the need for transfusion after total knee arthroplasty. Most literature has focused on intravenous (IV) administration of TXA, with less data available on the efficacy of topically administered TXA ...
M. Abdel, B. Chalmers, M. Taunton, M. Pagnano, R. Trousdale, R. Sierra, Yuo-yu Lee, F. Boettner, E. Su, S. Haas, M. Figgie, D. Mayman   +11 more
semanticscholar   +1 more source

Recent Advances in Topical Ocular Drug Delivery.

Journal of Ocular Pharmacology and Therapeutics, 2016
Topical ocular drug delivery has been considered to be an ideal route of administration for treatment of ocular diseases related to the anterior segment of the eye.
V. Yellepeddi, S. Palakurthi
semanticscholar   +1 more source

Clay nanosheets for topical delivery of RNAi for sustained protection against plant viruses

Nature Plants, 2017
N. Mitter, Elizabeth A. Worrall, K. Robinson, Peng Li, R. Jain, Christelle Taochy, Stephen J. Fletcher, B. Carroll, G. Lu, Gao Qing Lu, Z. Xu   +10 more
semanticscholar   +1 more source

Topical Retinoids in Acne Vulgaris: A Systematic Review

American Journal of Clinical Dermatology, 2019
S. Kolli, Danielle Pecone, Adrian Pona, A. Cline, S. Feldman   +4 more
semanticscholar   +1 more source

Topical treatments for skin cancer.

Advanced Drug Delivery Reviews, 2019
Jason K. Cullen, Jacinta L. Simmons, P. Parsons, G. Boyle   +3 more
semanticscholar   +1 more source