Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Genetic Characterization of RNA Recognition Motif (RRM)-Containing Genes in Coconut Palm
RNA recognition motif (RRM)-containing proteins are important regulators involved in diverse cellular processes, including splicing, stability, transport, and translation of transcripts.
Shazia Rehman +11 more
doaj +1 more source
An Overview of Tissue Engineering as an Alternative for Toxicity Assessment
Tissue engineering is a multidisciplinary field that combines aspects of biology, material sciences, engineering and medicine - the ultimate goal being able to fabricate replacement tissues and/or organs for an ageing population.
Mathew Garrod, David Yi San Chau
doaj +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
A within farm clinical trial to compare two treatments (parenteral antibacterials and hoof trimming) for sheep lame with footrot [PDF]
From observational studies, farmers who use parenteral antibacterials to promptly treat all sheep with footrot (FR) or interdigital dermatitis (ID) have a prevalence of lameness of
Abecia +38 more
core +2 more sources
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Evolutionary Insights and Flowering Regulation of SPLs in Coconut Palm
Squamosa Promoter-Binding Protein Like (SPL) is a critical transcription factor that plays a significant role in regulating plant growth and development.
Runan Chen +11 more
doaj +1 more source
Clinical translation of choline and geranic acid deep eutectic solvent
Choline geranate deep eutectic solvent/ionic liquid (CAGE) has shown several desirable therapeutic properties including antimicrobial activity and ability to deliver drugs transdermally in research laboratories.
Justin Ko +5 more
doaj +1 more source
Activity In Vitro of Clotrimazole against Canine Methicillin-Resistant and Susceptible Staphylococcus pseudintermedius [PDF]
Emergence of multidrug-resistance in Staphylococcus pseudintermedius (SP) has increased interest in topical therapy as an alternative to systemic antibiotics in canine pyoderma.
Bond, R, Frosini, S-M
core +3 more sources

