Results 171 to 180 of about 28,018 (262)

Effectiveness and Safety of Once‐Weekly Semaglutide 2.4 mg in Korean Adults With Obesity or Overweight: A Multicenter Retrospective Real‐World Study (RE‐SEMA‐K Study)

open access: yesDiabetes/Metabolism Research and Reviews, Volume 42, Issue 8, November 2026.
ABSTRACT Aims To evaluate the effectiveness and treatment patterns of once‐weekly semaglutide 2.4 mg in South Korean adults with overweight or obesity in real‐world practice. Materials and Methods This multicenter retrospective study analysed electronic medical records from 17 centres in South Korea.
Yu‐Jin Kwon   +21 more
wiley   +1 more source

The Impact of Outcome Measures for Responder Analyses in Placebo‐Controlled Trials of Pharmacological Treatments for Neuropathic Pain

open access: yesEuropean Journal of Pain, Volume 30, Issue 10, November 2026.
ABSTRACT Background Dichotomous responder outcomes, including ≥ 30% and ≥ 50% pain reduction, patient‐reported pain relief, and Patient Global Impression of Change (PGIC), are widely used in trials assessing interventions for neuropathic pain and have been suggested to be comparable, but their differences and influence on estimated treatment effects ...
Nanna Brix Finnerup   +28 more
wiley   +1 more source

Consensus Guidelines for Diagnosis and Management of Pyruvate Dehydrogenase Complex Deficiency

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Primary pyruvate dehydrogenase complex deficiency (PDCD) comprises a group of monogenic disorders caused by pathogenic variants in genes encoding subunits of, or regulatory components affecting, the pyruvate dehydrogenase complex. The clinical phenotype spans a broad continuum, ranging from early onset congenital lactic acidosis to infantile ...
Nandaki Keshavan   +23 more
wiley   +1 more source

Antiseizure Medication Dispensing Before and After Initiation of Antidementia Medicines: A Population‐Based Matched Cohort Study

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 11, November 2026.
ABSTRACT Purpose Seizures and behavioural and psychiatric features may prompt antiseizure medication (ASM) use in dementia. We examined whether increased ASM dispensing precedes or follows initiation of antidementia treatment to inform hypotheses about when these indications emerge.
Osvaldo P. Almeida   +4 more
wiley   +1 more source

Topiramate-Induced Fanconi Syndrome: A Case Report. [PDF]

open access: yesKidney Med
Berlinkova D   +3 more
europepmc   +1 more source

Efficacy and safety of pharmacological interventions for the treatment of cocaine use disorder: A systematic review and network meta‐analysis

open access: yesAddiction, Volume 121, Issue 11, Page 2897-2958, November 2026.
Abstract Background and aims Cocaine use disorder (CUD) is an increasingly widespread concern worldwide. Various pharmacological treatments have been investigated for CUD, but their efficacy remains unclear, and none have been licensed for treatment.
Craig Paterson   +13 more
wiley   +1 more source

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