Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi +6 more
wiley +1 more source
Drug-resistant Epilepsy: Which Drugs are Substrates of P-glycoprotein and Which are Not? [PDF]
Curr NeuropharmacolAylón Val J, Hernando-Requejo V.
europepmc +1 more source
Resolution of generalized tonic seizures following focal ablative or resective surgery
Epileptic Disorders, Volume 28, Issue 2, Page 333-343, April 2026.Abstract Objective Focal brain lesions may underlie generalized tonic seizures, as seen in Lennox–Gastaut syndrome, by engaging bilateral neural networks. However, this seizure type is often not considered surgically remediable. Here, we describe the resolution of apparent electroclinically classic generalized tonic seizures in children originating ...
Sem L. Kampman +3 more
wiley +1 more source
Dynamic associations between cannabis use and sleep in adolescents and young adults during a cannabis intervention trial. [PDF]
J Res AdolescParnes JE +3 more
europepmc +1 more source
Epileptic Disorders, Volume 28, Issue 2, Page 344-358, April 2026.Abstract Objective To summarize the electro‐clinical and genetic characteristics of children with Mowat–Wilson syndrome (MWS). Methods This study is a hospital‐based case series analyzing clinical data from 31 pediatric patients with MWS and epilepsy treated at Peking University First Hospital between June 2020 and December 2024.
Yi Ju, Tao‐yun Ji
wiley +1 more source
Effects of Two Boron-Containing Compounds Structurally Related to Topiramate on Three Models of Drug-Induced Seizures in Mice. [PDF]
Pharmaceuticals (Basel)Valenzuela-Schejtman Y +9 more
europepmc +1 more source
Epileptic Disorders, Volume 28, Issue 2, Page 488-495, April 2026.Abstract Epilepsy surgery remains the most effective treatment for focal drug‐resistant epilepsy, and stereoelectroencephalography (SEEG) is increasingly used to define the epileptogenic‐zone network (EZN) and guide curative or palliative interventions.
Ionuț‐Flavius Bratu +4 more
wiley +1 more source
Medication overuse headache: position statement of specialized headache centers in Brazil. [PDF]
Front Pain Res (Lausanne)Krymchantowski AV +11 more
europepmc +1 more source
Executive functions and self‐limited epilepsy with centro‐temporal spikes: A scoping review
Epileptic Disorders, Volume 28, Issue 2, Page 275-294, April 2026.Abstract Executive functions are a set of high‐level cognitive processes necessary for planning, organization, decision‐making, self‐control, and attention, and are carried out in the anterior frontal lobes. An impairment in executive functioning might present as difficulties in planning and organizing activities, in attention and concentration, in ...
Edoardo Fino +6 more
wiley +1 more source
Unusual case of topiramate-induced auditory-visual synaesthesia in a non-synaesthete young adult: a case report. [PDF]
AME Case RepYaqub Y, Ramkumar P, Jerjes W.
europepmc +1 more source