Results 201 to 210 of about 36,003 (284)

Attention and Executive Functions Are the Most Vulnerable Cognitive Domains in Patients With Drug‐Resistant Epilepsy Prior to Neurostimulation Therapy

Brain and Behavior, Volume 16, Issue 4, April 2026.
More than one‐third of the patients with drug‐resistant epilepsy (DRE) referred for neurostimulation therapies exhibited cognitive impairment across all four assessed domains. Deficits in attention and executive functions were the most prevalent and severe, affecting 66% of the cohort.
Niina Lähde, Pabitra Basnyat, Hanna Lehtinen, Eija Rosti‐Otajärvi, Leena Kämppi, Jukka Peltola   +5 more
wiley   +1 more source

Topiramate Enhances GABAergic Tone to Orexigenic Neuropeptide Y/Agouti-Related Peptide (NPY/AgRP) Neurons. [PDF]

Obesity (Silver Spring)
Minbashi Moeini M, Lavoie O, Caron A, Williams KW, Michael NJ.   +4 more
europepmc   +1 more source

New Publications and Presentations from the Department of Health Policy [PDF]

, 2007

core   +1 more source

Anticonvulsant Effects of Citronellal, Daidzin, and Phytol, Possibly Through GABAA Receptor and Voltage‐Gated Sodium Channel Interaction Pathways: In Vivo and In Silico Studies

Brain and Behavior, Volume 16, Issue 4, April 2026.
Citronellal, daidzin, and phytol exert significant anticonvulsant effects in a chick seizure model by enhancing GABAergic transmission and blocking voltage‐gated sodium channels, with combination therapies showing enhanced efficacy and a favorable safety profile.
Emon Mia, Md. Anisur Rahman, Md. Nasimul Haque Shipon, Moushumi Afroza Mou, Proma Mandal, Imam Hossen Rakib, Md. Abu Sayeed, Muhammad Torequl Islam, Md. Sakib Al Hasan, Mushtaq Ahmad Ansari   +9 more
wiley   +1 more source

The effect of combining surgical or endoscopic bariatric interventions with anti-obesity medication or probiotics on weight loss: a narrative review. [PDF]

Front Endocrinol (Lausanne)
de Waal JR, Nieuwdorp M, Gerdes VEA.
europepmc   +1 more source

Utility of Patch Testing, LTT, and HLA Genotyping in Identifying Culprit Drugs and Diagnosing Multiple Drug Hypersensitivity in Definite DRESS: A 10‐Year Cohort Study

Clinical and Translational Allergy, Volume 16, Issue 4, April 2026.
In a prospective cohort of patients with definite Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), multiple drug hypersensitivity syndrome (MDHS) was associated with increased disease severity and a higher frequency of human leukocyte antigen (HLA) risk alleles.
Derya Ünal, Osman Ozan Yeğit, Semra Demir, Bircan Erden, Pelin Korkmaz, Fatma Savran Oğuz, Çiğdem Kekik Çınar, Sonay Temurhan, Deniz Eyice Karabacak, Ilkim Deniz Toprak, Zeynep Kılınç, Mehmet Sait Yordam, Nevzat Kahveci, Merve Hörmet İğde, Şule Çelik Kamacı, Ayşe Feyza Aslan, Mehmet Emin Sezgin, Esra Kaya, Leyla Bölek, Raif Coşkun, Müge Olgaç, Nida Öztop, Aslı Gelincik   +22 more
wiley   +1 more source

The Effect of Psychotropic Medications on Glaucoma Risk and Intraocular Pressure: A Bayesian Meta-Analysis. [PDF]

CNS Drugs
Jannini TB, Alisi L, Giovannetti F, Armentano M, Di Lorenzo G, Niolu C, Siracusano A.   +6 more
europepmc   +1 more source

Building a Better Innovation System: Combining Facially Neutral Patent Standards withTherapeutics Regulation [PDF]

, 2008
Rai, Arti K.
core   +1 more source

The Mechanism Underlying the Abnormal Expression of α‐Synuclein in the Cortical Lesions of Patients With FCD Type IIb and TSC

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
The mTOR/GLT‐1 pathway abnormality induces α‐synucleinopathy, contributing to seizures in FCD lesions, which were rescued by treatment with the mTOR inhibitor Rapa or the GLT‐1 enhancer Cef. Intracerebroventricular α‐syn administration attenuated PTZ‐induced seizures in FCD models.
Li Zhang, Jian‐Ping Song, Jun Huang, Ping Liang, Hui Yang, Chun‐Qing Zhang, Kai‐Feng Shen   +6 more
wiley   +1 more source

Neurodevelopmental Teratogenicity of Antiseizure Medications: The Good, the Bad, and Unknown. [PDF]

Epilepsy Curr
Kobayashi E.
europepmc   +1 more source