Results 141 to 150 of about 175,878 (262)

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

Water Versus Land on Temperate Rocky Planets. [PDF]

Space Sci Rev
Guimond CM, Spohn T, Berdyugina S, Byrne PK, Coltice N, Glaser DM, Lingam M, Lineweaver CH, Cawood PA.   +8 more
europepmc   +1 more source

Precise Control of Drug Release in Machine Learning‐Designed Antibody‐Eluting Implants for Postoperative Scarring Inhibition in Glaucoma

Advanced Healthcare Materials, EarlyView.
We developed a micro‐sized, biocompatible implant for postoperative sustained delivery of anti‐fibrotic antibodies in glaucoma surgery. Machine learning‐guided optimization of polymer composition, implant geometry, and porosity enabled precise control of drug release.
Mengqi Qin, Wenbing Jiang, Kai Xin Thong, Zeynep Ulker, Brihitejas Patel, Cynthia Yu‐Wai‐Man   +5 more
wiley   +1 more source

One-Year Outcomes of Topography-Guided LASIK for Myopia and Astigmatism. [PDF]

J Ophthalmol
Wei S, Zheng Y, Fu C, Zhang L, Hu Y, Dong Y, Ma D, Zhai C.   +7 more
europepmc   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Hormonal Modulation of Keratoconus: A Systematic Review and Screening Strategy for At-Risk Populations. [PDF]

Ophthalmol Sci
Ashraf M, Shoraka E, Shahabi S, Ghalibafan S, Ahmed A, Rad MK, Bouchard CS, Saeed HN.   +7 more
europepmc   +1 more source

SiO2‐CaOCME/Poly(Tetrahydrofuran)/Poly(Caprolactone) 3D‐Printed Scaffolds Drive Human‐Bone Marrow Stromal Cell Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
3D printed hybrid scaffolds combining bioactive silica–calcium chemistry with elastic polymers guide human bone stem cells to form bone. The scaffolds support cell survival, organization, and invasion while releasing osteogenic ions. Together, architecture and composition drive bone‐specific gene expression, extracellular matrix organization, and ...
David R. Sory, Agathe C.M. Heyraud, Julian R. Jones, Sara M. Rankin   +3 more
wiley   +1 more source

Trends in the Prevalence of Adolescent Idiopathic Scoliosis in a Japanese Prefecture: A 25-Year Population-Based School Screening Study Using Moiré Topography. [PDF]

Global Spine J
Morino T, Murakami Y, Kinoshita T, Hino M, Misaki H, Yamaoka S, Kutsuna T, Takao M.   +7 more
europepmc   +1 more source

In Vivo Skin 3‐D Surface Reconstruction and Wrinkle Depth Estimation Using Handheld High Resolution Tactile Sensing

Advanced Healthcare Materials, EarlyView.
A compact handheld GelSight probe reconstructs in vivo 3‐D skin topography with micron‐level precision using a custom elastic gel and a learning‐based surface normal to height map pipeline. The device quantifies wrinkle depth across various body locations and detects changes in wrinkle depth following moisturizer application.
Akhil Padmanabha, Arpit Agarwal, Catherine Li, Austin Williams, Dinesh K. Patel, Sankalp Chopkar, Achu Wilson, Ahmet Ozkan, Wenzhen Yuan, Sonal Choudhary, Arash Mostaghimi, Zackory Erickson, Carmel Majidi   +12 more
wiley   +1 more source

Immunomodulatory topographies regulate myofibroblast differentiation and influence fibrous encapsulation of glaucoma drainage devices. [PDF]

Bioact Mater
Sudarsanam PK, van Mechelen RJS, Kuijpers TJM, Bertens CJF, Alsema E, Verbakel J, Beijer NRM, Beckers HJM, de Boer J.   +8 more
europepmc   +1 more source