Results 71 to 80 of about 7,249,127 (302)

Topological Data Analysis and Clustering

open access: yes, 2023
This article is intended to be a chapter for a ...
openaire   +2 more sources

Feasibility of topological data analysis for event-related fMRI [PDF]

open access: yesNetwork Neuroscience, 2019
Recent fMRI research shows that perceptual and cognitive representations are instantiated in high-dimensional multivoxel patterns in the brain. However, the methods for detecting these representations are limited. Topological data analysis (TDA) is a new
Cameron T. Ellis   +4 more
doaj   +1 more source

Statistical topological data analysis using persistence landscapes [PDF]

open access: yes, 2015
We define a new topological summary for data that we call the persistence landscape. Since this summary lies in a vector space, it is easy to combine with tools from statistics and machine learning, in contrast to the standard topological summaries ...
Bubenik, Peter
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Probing omics data via harmonic persistent homology

open access: yesScientific Reports
Identifying molecular signatures from complex disease patients with underlying symptomatic similarities is a significant challenge in the analysis of high-dimensional multi-omics data.
Davide Gurnari   +5 more
doaj   +1 more source

Induction Motor Eccentricity Fault Detection and Quantification Using Topological Data Analysis

open access: yesIEEE Access
In this paper, we propose a topological data analysis (TDA) method for the processing of induction motor stator current data, and apply it to the detection and quantification of eccentricity faults. Traditionally, physics-based models and involved signal
Bingnan Wang   +3 more
semanticscholar   +1 more source

Topological Data Analysis as a New Tool for EEG Processing

open access: yesFrontiers in Neuroscience, 2021
Electroencephalography (EEG) is a widely used cerebral activity measuring device for both clinical and everyday life applications. In addition to denoising and potential classification, a crucial step in EEG processing is to extract relevant features ...
Xiaoqi Xu, Nicolas Drougard, R. Roy
semanticscholar   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Confinement and short distance physics

open access: yes, 2000
We consider non-perturbative effects at short distances in theories with confinement. The analysis is straightforward within the Abelian models in which the confinement arises on classical level.
Akhoury   +17 more
core   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez   +5 more
wiley   +1 more source

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