Results 41 to 50 of about 3,589,353 (244)
Systemic neuropsychology: toward a contemporary theory of topological functional systems
Frontiers in PsychiatryThis article proposes a formalization of psychological functions as Topological Functional Systems, drawing on the historical–cultural tradition and functional systems theory, and integrating them with tools from contemporary topological dynamics. First,
Julián Andrés Guiral +1 more
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Observation of Anderson phase in a topological photonic circuit
Physical Review Research, 2022 Disordered systems play a central role in condensed matter physics, quantum transport, and topological photonics. It is commonly believed that a topological nontrivial phase would turn into a trivial phase where the transport vanishes under the effect of
Jun Gao +8 more
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Dynamical triangulation with fluctuating topology [PDF]
Nuclear Physics B - Proceedings Supplements, 1995 3 pages, LaTeX2e source with postscript result One reference ...
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Annals of Pure and Applied Logic, 2009 Phil Kremer has a very elegant and succinct style of presentation. In this paper, he presents four temporal extensions of the modal logic S5 interpreted on topological spaces. In this setting, the interpretation of a formula is a subset of a topological space.
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RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Topological Dynamics of Groupoid Actions [PDF]
, 2022 Some basic notions and results in Topological Dynamics are extended to continuous groupoid actions in topological spaces. We focus mainly on recurrence properties.
Flores, Felipe, Mantoiu, Marius
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Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source