Results 231 to 240 of about 740,617 (344)
Tumor‐Tissue Boundaries as Instructive Interfaces in Breast Cancer Cell Invasion
Tumor‐tissue boundaries reprogram metastatic breast cancer cells, enhancing invasiveness through an instructive, not permissive, mechanism. Using a 3D collagen I‐based tumor‐tissue interface model, single‐cell analysis, and simulations, this study shows that all cells can transmigrate without selective filtering, highlighting a targetable process in ...
Cornelia Clemens +6 more
wiley +1 more source
Topological phases of extended Su-Schrieffer-Heeger-Hubbard model. [PDF]
Chang PJ +6 more
europepmc +1 more source
The ANGPTL8/PIRB/ALOX5AP axis mediates liver‐kidney crosstalk. Hepatocytes secrete ANGPTL8, which binds to CCR2+PIRB+ macrophages in the kidneys, affecting the expression of ALOX5AP and enhancing the activation of these macrophages. Activated cells produce TGF‐β, IL‐6, and IL‐23, driving Th17 activation and promote the formation of myofibroblasts ...
Shuqi Wei +18 more
wiley +1 more source
Molecular characterization and information entropies of chevron-like graphene nanoribbons with chemical applications. [PDF]
Prabhu SM +3 more
europepmc +1 more source
Interpretation of RNA Universe and Coding Potential Using IntRNA
This study constructs a multi‐channel deep learning framework IntRNA to interpret RNA universe and coding potential. IntRNA consistently performed the best among existing methods in various benchmarks. Moreover, IntRNA’s interpretability is also validated by real‐world analysis, which found some features indicating long‐distance contact between ...
Yunxia Wang +8 more
wiley +1 more source
Hypergraph Semi-Supervised Contrastive Learning for Hyperedge Prediction Based on Enhanced Attention Aggregator. [PDF]
Xie H, Song C, Shao H, Wang L.
europepmc +1 more source
Topological feedback entropy for nonlinear stabilization
Girish N. Nair +3 more
openalex +1 more source
Hypoxia triggers lactylation of PRMT1 at K134/K145, enhancing its methyltransferase activity to asymmetrically dimethylate vimentin R64. This post‐translational cascade promotes vimentin filament assembly, cytoskeletal remodeling, and tumor metastasis, with PRMT1 inhibition (MS023) reducing metastatic colonization.
Jia Zhou +16 more
wiley +1 more source

