Results 51 to 60 of about 5,113,672 (306)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Mathematics, 2023 This paper initiates the study of the mathematical aspects of the ad-hoc Lanzhou index. If G is a graph with the vertex set {x1,…,xn}, then the ad-hoc Lanzhou index of G is defined by Lz˜(G)=∑i=1ndi(n−1−di)2, where di represents the degree of the vertex ...
Akbar Ali +3 more
doaj +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Journal of Inequalities and Applications, 2017 Topological indices are the mathematical tools that correlate the chemical structure with various physical properties, chemical reactivity or biological activity numerically.
Muhammad Imran +3 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
FEBS Letters, EarlyView.Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
Properties of the forgotten index in bipolar fuzzy graphs and applications
Scientific ReportsTopological indices are the numbers that remain constant under graph automorphism. Topological indices describe a network’s connectivity, structure, and topological characteristics. These indices have many applications in crisp graphs.
Shaikh Ibrahim Abdullah +5 more
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Hosoya and Harary Polynomials of TOX(n),RTOX(n),TSL(n) and RTSL(n)
Discrete Dynamics in Nature and Society, 2019 In the fields of chemical graph theory, topological index is a type of a molecular descriptor that is calculated based on the graph of a chemical compound.
Lian Chen +5 more
doaj +1 more source
Index Theorem on Chiral Landau Bands for Topological Fermions
, 2021 Topological fermions as excitations from multidegenerate Fermi points have been attracting increasing interest in condensed matter physics. They are characterized by topological charges, and magnetic fields are usually applied in experiments for their ...
Zhao, Y. X. +3 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source