Results 51 to 60 of about 51,997 (309)
Journal of Inequalities and Applications, 2017 Topological indices are the mathematical tools that correlate the chemical structure with various physical properties, chemical reactivity or biological activity numerically.
Muhammad Imran +3 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Index theory and topological phases of aperiodic lattices [PDF]
, 2021 A Delone set is a uniformly discrete and relatively dense subset of Euclidean space $\mathbb{R}^{d}$. As such they constitute a mathematical model for a general solid material.
Mesland, Bram
core
Topological Descriptors on Some Families of Graphs
Journal of Chemistry, 2021 In view of the successful applications of graph theory, relationships between the biological activity and chemical structure have been developed. One of the popular topics in graph theory is problems relating to topological indices.
Iftikhar Ahmad +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
GENERALIZED TOPOLOGICAL TRANSITION MATRIX. [PDF]
, 2016 . This article represents a major step in the unification of the theory of algebraic, topological and singular transition matrices by introducing a definition which is a generalization that encompasses all of the previous three.
de Rezende, Ketty A. +8 more
core +1 more source
Degree-Based Graph Entropy in Structure–Property Modeling
Entropy, 2023 Graph entropy plays an essential role in interpreting the structural information and complexity measure of a network. Let G be a graph of order n. Suppose dG(vi) is degree of the vertex vi for each i=1,2,…,n.
Sourav Mondal, Kinkar Chandra Das
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Hosoya and Harary Polynomials of TOX(n),RTOX(n),TSL(n) and RTSL(n)
Discrete Dynamics in Nature and Society, 2019 In the fields of chemical graph theory, topological index is a type of a molecular descriptor that is calculated based on the graph of a chemical compound.
Lian Chen +5 more
doaj +1 more source
Topological invariant and anomalous edge modes of strongly nonlinear systems
Nature Communications, 2022 Topological phases are challenging to identify in systems with general, strong nonlinearities. Here, the authors establish the analytic methodology that defines the topological invariant of nonlinear normal modes.
Di Zhou +3 more
doaj +1 more source