Results 71 to 80 of about 51,997 (309)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez   +5 more
wiley   +1 more source

Empirical predictions of an intrinsically disordered protein theory approach to glycan/lectin reaction kinetics [PDF]

open access: yes, 2012
Newly-developed methods from the theory of intrinsically disordered proteins can be applied to the flexible glycan structures that coat cellular surfaces and provide rich channels for biological information transmission.
Rodrick Wallace
core   +1 more source

The topological period-index problem over 8-complexes, II [PDF]

open access: yes, 2020
We complete the study of the topological period-index problem over 8dimensional finite CW complexes started in a preceding paper. More precisely,we determine the sharp upper bound of the index of a topological Brauer class$\alpha\in H^3(X;\mathbb{Z ...
Gu, X. ; https://orcid.org/
core   +2 more sources

Non-kekulean benzenoid hydrocarbon: physico-chemical properties for benzenoid hydrocarbon using topological indices and mpolynomial [PDF]

open access: yesComputational Algorithms and Numerical Dimensions
Topological indices are the numerical values that are connected to subatomic graphs in order to create the quantitative structure activity and structure attribute of a chemical compound and non-chemical graphs.
Anns Uzair   +2 more
doaj   +1 more source

On the Inverse Symmetric Division Deg Index of Unicyclic Graphs

open access: yesComputation, 2022
The symmetric division deg (SDD) index is among the 148 discrete Adriatic indices that were developed about a decade ago. Motivated by the success of the SDD index, Ghorbani et al.
Abeer M. Albalahi, Akbar Ali
doaj   +1 more source

Factorising the 3D topologically twisted index [PDF]

open access: yesJournal of High Energy Physics, 2017
Exploramos la integración de rutas, sobre el contorno de configuraciones de campos hermíticas (no auxiliares), de $$ \mathcal{N}=2 $$ Teoría de la materia de Chern-Simons (TTCSM) topológicamente retorcida en $$ {\mathbb{S}}_2 $$ veces por segmento.
openaire   +4 more sources

On the Lightweight Potential of Laser Additive Manufactured NiTi Triply Periodic Minimal Sheet Lattices

open access: yesAdvanced Engineering Materials, EarlyView.
This study explores the lightweight potential of laser additive‐manufactured NiTi triply periodic minimal surface sheet lattices. It systematically investigates the effects of relative density and unit cell size on surface quality, deformation recovery, compression behavior, and energy absorption.
Haoming Mo   +3 more
wiley   +1 more source

Microstructure Evolution of a VMnFeCoNi High‐Entropy Alloy After Synthesis, Swaging, and Annealing

open access: yesAdvanced Engineering Materials, EarlyView.
The synthesis and processing (rotary swaging and annealing) of the novel VMnFeCoNi alloy is investigated, alongside the estimation of the grain size effect on hardness. Analysis of a wide grain size range of recrystallized microstructures (12–210 µm) reveals a low annealing twin density.
Aditya Srinivasan Tirunilai   +6 more
wiley   +1 more source

Solitons in low-dimensional sigma models [PDF]

open access: yes, 1997
The aim of this thesis is to study topological soliton solutions in classical field theories, called sigma models, on a three-dimensional space. In chapter 1 we review the general field-theoretical framework of classical soliton solutions and exemplify ...
Gladikowski, J., Gladikowski, Jens
core  

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