Results 131 to 140 of about 29,264 (279)
Advanced Science, EarlyView.SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang +8 more
wiley +1 more source
Brain and BehaviorIntroduction Anti‐N‐methyl‐D‐aspartate receptor (anti‐NMDAR) encephalitis is a type of autoimmune disorder manifesting in neurologic, cognitive, and psychological abnormalities, yet its neurological basis remains obscure.
Rui Qian +7 more
doaj +1 more source
Inhibitory Decay and Supercritical Brain Dynamics During Sleep Deprivation
Advanced Science, EarlyView.Sleep deprivation progressively shifts human brain dynamics from near‐critical toward supercritical states, as revealed by neuronal avalanche analysis of resting‐state fMRI. These changes track subjective sleep pressure rather than vigilance lapses and show marked network heterogeneity. A circuit model suggests that reduced inhibitory efficacy provides
Dai Zhang +6 more
wiley +1 more source
Topological methods in abstract algebra. cohomology theory of groups [PDF]
Bulletin of the American Mathematical Society, 1949 openaire +3 more sources
Flexoelectricity in Photoconversion: Fundamentals, Materials, and Outlooks
Advanced Science, EarlyView.Mechanical bending of a flexible cantilever induces a strain gradient in the photoactive material. The resulting flexoelectric field couples with photovoltaic and photoconductive effects, modulating charge generation, separation, and collection. A comparative analysis of oxide perovskites, halide perovskites, and two‐dimensional materials is presented,
Xiang Huang, Feng Li, Rongkun Zheng
wiley +1 more source
A Positive Theory of Network Connectivity [PDF]
This paper develops a positive theory of network connectivity, seeking to explain the micro-foundations of alternative network topologies as the result of self-interested actors. By building roads, landowners hope to increase their parcelsÕ accessibility
Arthur Huang, David Levinson
core
Parity and generalized multiplicity [PDF]
, 1991 Assuming that X and Y are Banach spaces and that T is a path of linear Fredholm operators with invertible endpoints, in [F-Pl] we defined a homotopy invariant "the parity of T .
Fitzpatrickp. +2 more
core
Health Science ReportsBackground and Aim There is compelling evidence that gray matter changes associated with migraine, which in turn may alter morphological network topology.
G.D.C.J. Prabhashana +5 more
doaj +1 more source
Book Review: The geometry and topology of Coxeter groups; Topological methods in group theory [PDF]
Bulletin of the American Mathematical Society, 2012 openaire +1 more source
Advanced Science, EarlyView.We investigate the geometry‐governed optoelectronic anisotropy arising from dielectric confinement in quasi‐1D γ‐GaS nanoribbons with intrinsically isotropic atomic structures. Dielectric mismatch between the nanoribbon and its surroundings leads to a general polarization‐dependent photoresponse during near‐field scattering.
Jiawei Jing +16 more
wiley +1 more source