Results 41 to 50 of about 36,818 (256)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Mining the Synergistic Core Allosteric Modules Variation and Sequencing Pharmacological Module Drivers in a Preclinical Model of Ischemia

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2018
Identifying the variation of core modules and hubs seems to be critical for characterizing variable pharmacological mechanisms based on topological alteration of disease networks.
Yingying Zhang   +8 more
doaj   +1 more source

Fundamental Groups of Topological R-Modules [PDF]

open access: yesTransactions of the American Mathematical Society, 1982
The main result of this paper is that if R R is a countable, Noetherian ring, then the underlying abelian group of every
openaire   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno   +19 more
wiley   +1 more source

Dysregulated Cholesterol Metabolism, Chronic Inflammation, and Disability in Severe Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks   +8 more
wiley   +1 more source

A Zariski Topology for Modules [PDF]

open access: yesCommunications in Algebra, 2011
Given a duo module $M$ over an associative (not necessarily commutative) ring $R,$ a Zariski topology is defined on the spectrum $\mathrm{Spec}^{\mathrm{fp}}(M)$ of {\it fully prime} $R$-submodules of $M$. We investigate, in particular, the interplay between the properties of this space and the algebraic properties of the module under consideration.
openaire   +2 more sources

Mitigating Creep Anisotropy and Enhancing Performance in Additively Manufactured Ni‐Based Superalloys: A Review

open access: yesAdvanced Engineering Materials, EarlyView.
Additive manufacturing introduces pronounced microstructural and crystallographic anisotropy in Ni‐based superalloys, resulting in orientation‐dependent creep deformation and damage. This review identifies the key microstructural origins of creep anisotropy, examines their influence on dominant deformation mechanisms, and highlights processing ...
Chandan Kumar   +3 more
wiley   +1 more source

Multi-Hypothesis Topological Isomorphism Matching Method for Synthetic Aperture Radar Images with Large Geometric Distortion

open access: yesRemote Sensing, 2021
The dramatic undulations of a mountainous terrain will introduce large geometric distortions in each Synthetic Aperture Radar (SAR) image with different look angles, resulting in a poor registration performance.
Runzhi Jiao   +3 more
doaj   +1 more source

On barrelled topological modules [PDF]

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1993
Some of the main theorems concerning ultrabarrelled topological vector spaces are extended to the context of topological modules.
openaire   +3 more sources

Functionalizing Micro‐to‐Mesoscopic Electrode Architectures for Regulating Electron Transfer Behaviors in Electrocatalysis

open access: yesAdvanced Functional Materials, EarlyView.
A systematic review is conducted to assess the influence of electrode architecture across micro‐ to mesoscopic length scales on electron‐transfer pathways in electrocatalysis. We discuss the structure‐activity relationships in electrocatalytic applications, including resource recovery and environmental remediation, and provide cost‐effective, efficient
Manshu Zhao   +6 more
wiley   +1 more source

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