Results 201 to 210 of about 935 (235)
From Stability to Chaos: A Complete Classification of the Damped Klein‐Gordon Dynamics
ABSTRACT We investigate the transition between stability and chaos in the damped Klein‐Gordon equation, a fundamental model for wave propagation and energy dissipation. Using semigroup methods and spectral criteria, we derive explicit thresholds that determine when the system exhibits asymptotic stability and when it displays strong chaotic dynamics ...
Carlos Lizama +2 more
wiley +1 more source
This integrated systems biology study of 2847 exposure‐related genes identifies a conserved 647‐gene core and CYP1B1 hub across cigarette smoke, ozone, and PM2.5. Three key pathways converge, enabling computational repurposing of 15 drug candidates (e.g., NRF2 activators) for environmentally induced COPD.
Fakher Rahim +2 more
wiley +1 more source
Advancing Heliophysics and Space Weather Modeling Through Open Science
Abstract We present a community‐wide effort to develop a strategy and action plan to advance heliophysics and space weather modeling through open science. While open science has the potential to enhance the quality and pace of scientific discovery, its application to scientific modeling requires more careful consideration regarding open data and open ...
C. Corti +87 more
wiley +1 more source
SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu +16 more
wiley +1 more source
ABSTRACT This study aimed to elucidate the mechanism of action of Schisandrin A in the intervention of triple‐negative breast cancer (TNBC). Through the application of network pharmacology and the integration of targets from multiple databases, the research identified 128 overlapping targets between Schisandrin A and TNBC.
Meng Xu +6 more
wiley +1 more source
Exploring the Potential of Calebin‐A in Targeting Obesity‐Related Genes and Pathways
ABSTRACT Obesity is a global health crisis affecting millions, associated with metabolic disorders such as type 2 diabetes and cardiovascular disease. Calebin‐A, a bioactive compound derived from Curcuma species, has shown promise in managing obesity and its complications.
Ali Mahmoudi +4 more
wiley +1 more source
Twisted ambidexterity in equivariant homotopy theory
Abstract We develop the concept of twisted ambidexterity in a parametrized presentably symmetric monoidal ∞$\infty$‐category, which generalizes the notion of ambidexterity by Hopkins and Lurie and the Wirthmüller isomorphisms in equivariant stable homotopy theory, and is closely related to Costenoble–Waner duality.
Bastiaan Cnossen
wiley +1 more source
A novel 3‐hydroxy‐2,3‐dihydroquinazolinone scaffold is identified as a cell‐active KDM4A inhibitor through an orthogonal screening cascade minimizing assay interference. Integrated biochemical, biophysical, and proteomic validation reveals compound 6i as a bona fide binder that increases H3K9 methylation in cells, highlighting both a promising ...
Alessandra Feoli +13 more
wiley +1 more source
Exact Results in ABJM Theory from Topological Strings
Marcos Mariño, Pavel Putrov
openalex +1 more source
Strong-weak symmetry and quantum modularity of resurgent topological strings on local $\mathbb{P}^2$ [PDF]
Veronica Fantini, Claudia Rella
openalex +1 more source

