Results 131 to 140 of about 283,214 (276)

Enhanced Activities of OCT4 and SOX2 Promote Epigenetic Reprogramming by Shortening G1 Phase

open access: yesAdvanced Science, EarlyView.
Fusing the VP16 domain to OCT4 and SOX2 (OvSvK) enhances iPSC generation by activating downstream targets, including those regulating the cell cycle. This accelerates reprogramming by shortening the G1 phase and reducing H3K27me3 levels. Modulating Ccnd1, Cdkn2a, and Ccne1 improves efficiency, linking cell cycle to epigenetic remodeling.
Lin Guo   +17 more
wiley   +1 more source

A bright future for topological acoustics. [PDF]

open access: yesNat Commun
Alù A, Daraio C, Deymier P, Ruzzene M.
europepmc   +1 more source

Topology Augmented with Geometry in the Assembly of Structural Databases: Kagome Intermetallics

open access: yesAdvanced Science, EarlyView.
The combination of topological filtering with geometrical restraints reliably screens for kagome layers within intermetallic compounds. The resulting comprehensive list of kagome net‐containing intermetallics can be reviewed to identify examples of interest for particular investigations and also used to build ML models to guide the search for further ...
Nataliya L. Gulay   +8 more
wiley   +1 more source

Cracking the Valence Code: Patterned Facial Kinematics and Neural Signatures of Emotional Expressions in Mice

open access: yesAdvanced Science, EarlyView.
An AI‐powered system decodes emotional valence from mouse facial expressions, identifying ear dynamics as key indicators. By integrating facial kinematics with synchronized neural recordings, this approach establishes a direct link between behavior and brain activity, advancing automated emotion recognition in animal models.
Yujia Chen   +9 more
wiley   +1 more source

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