Results 51 to 60 of about 518,702 (319)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Nucleosomal DNA has topological memory
Nature CommunicationsOne elusive aspect of the chromosome architecture is how it constrains the DNA topology. Nucleosomes stabilise negative DNA supercoils by restraining a DNA linking number difference (∆Lk) of about −1.26.
Joana Segura +5 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Topology in information theory in topology
Theoretical Computer Science, 2008 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
BarekengThe rainbow connection was first introduced by Chartrand in 2006 and then in 2009 Krivelevich and Yuster first time introduced the rainbow vertex connection. Let graph be a connected graph.
Muhammad Ilham Nurfaizi Annadhifi +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The Topology of Branching Universes [PDF]
, 2005 The purpose of this paper is to survey the possible topologies of branching space-times, and, in particular, to refute the popular notion in the literature that a branching space-time requires a non-Hausdorff ...
McCabe, Gordon, Gordon Mccabe
core
Large Sets in Boolean and Non-Boolean Groups and Topology
Axioms, 2017 Various notions of large sets in groups, including the classical notions of thick, syndetic, and piecewise syndetic sets and the new notion of vast sets in groups, are studied with emphasis on the interplay between such sets in Boolean groups.
Ol’ga V. Sipacheva
doaj +1 more source
Primary decomposition in the smooth concordance group of topologically slice knots
Forum of Mathematics, Sigma, 2021 We address primary decomposition conjectures for knot concordance groups, which predict direct sum decompositions into primary parts. We show that the smooth concordance group of topologically slice knots has a large subgroup for which the conjectures ...
Jae Choon Cha
doaj +1 more source