Results 41 to 50 of about 171,442 (263)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Topology Control Algorithm in Heterogeneous Wireless Sensor Network with Energy Supply

Dianxin kexue, 2015
In view of the problem that current algorithm mainly research on topology construction or topology maintenance separately，a topology control algorithm based on two processes combined was proposed，which was adaptive to the network with heterogeneous ...
Chenming Ma, Wanliang Wang, Zhen Hong, Xinwei Yao   +3 more
doaj  

Topological Control on Silicates’ Dissolution Kinetics [PDF]

Langmuir, 2016
Like many others, silicate solids dissolve when placed in contact with water. In a given aqueous environment, the dissolution rate depends highly on the composition and the structure of the solid, and can span several orders of magnitude. Although the kinetics of dissolution depends on the complexities of both the dissolving solid and the solvent, a ...
Pignatelli, Isabella, Kumar, Aditya, Bauchy, Mathieu, Sant, Gaurav   +3 more
openaire   +5 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Topology control in VANET and capacity estimation [PDF]

2013 IEEE Vehicular Networking Conference, 2013
Some safety applications using VANET exchange a large amount of data, and consequently require an important network capacity. In this paper, we focus on extended perception map applications, that use information from local and distant sensors to offer driving assistance (autonomous driving, collision warning, etc).
Giang, Anh Tuan, Busson, Anthony, Lambert, Alain, Gruyer, Dominique   +3 more
openaire   +2 more sources

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Probability Model Based Energy Efficient and Reliable Topology Control Algorithm

Energies, 2016
Topology control is an effective method for improving the performance of wireless sensor networks (WSNs). Many topology control algorithms can achieve high energy efficiency by dynamically changing the transmission range of nodes.
Ning Li, Jose-Fernan Martinez-Ortega, Lourdes Lopez Santidrian, Juan Manuel Meneses Chaus   +3 more
doaj   +1 more source

Controlled homotopy topological structures [PDF]

Pacific Journal of Mathematics, 1988
Let \(P: E\to B\) be a locally trivial bundle with fibre F, where E and B are closed topological manifolds, dim \(E\geq 5\), and B admits a handlebody structure. This paper studies controlled homotopy topological structures on E, control being measured in B. Such structures can be constructed as a semi-simplicial complex S(p).
openaire   +3 more sources