Results 61 to 70 of about 7,048 (213)
Advanced Science, EarlyView.The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source
Decoupling configurations from moduli spaces of manifolds
, 2022 We consider moduli spaces of d-dimensional manifolds with embedded particles and discs. In such a moduli space, the location of the particles and discs is constrained by the d-dimensional manifold.
Basualdo Bonatto, Luciana
core +1 more source
Advanced Science, EarlyView.ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen +18 more
wiley +1 more source
Advanced Science, EarlyView.We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu +11 more
wiley +1 more source
Topics in the General Topology of Non-metric Manifolds
, 2014 The main core of this thesis is the general topology of non-metrisable manifolds. Although our emphasis was studying non-metrisable topological manifolds, we did not hesitate to consider topological properties which are useful in studying manifolds in a ...
Mardani, Afshin
core
Diverse Landscape of Tunable Magnetic, Topological, and Ferroelectric States in 2D Ti3Se3Te2
Advanced Science, EarlyView.Ti3Se3Te2 emerges as a multifunctional 2D van der Waals platform. The monolayer is a dynamically stable ferromagnetic quantum anomalous Hall insulator. In bilayers, two stacking configurations yield distinct phases: AA‐stacking hosts an altermagnetic quantum spin Hall insulator, while AA′‐stacking exhibits three‐state in‐plane ferroelectricity ...
Jiangtao Yu +5 more
wiley +1 more source
Holomorphic curves and minimal surfaces in Kähler manifolds [PDF]
Our work is concerned with the relation between a complex differential geometric property, namely holomorphicity, and a metric one, namely to be conformal and minimal, of immersions (possibly branched) of Riemann surfaces into Kahler manifolds. A well
Arezzo, Claudio
core
Surfaces, submanifolds, and aligned fox reimbedding in non-Haken 3-manifolds [PDF]
, 2005 Understanding non-Haken 3-manifolds is central to many current endeavors in 3-manifold topology. We describe some results for closed orientable surfaces in non-Haken manifolds, and extend Fox's theorem for submanifolds of the 3-sphere to submanifolds of ...
Thompson, A, Scharlemann, M
core
Advanced Science, EarlyView.Interpretable machine learning reveals how composition and processing govern the formation and microstructural burden of Fe‐rich intermetallic compounds in recycled Al–Si–Fe–Mn alloys. By separating morphology selection from morphology‐conditioned burden partitioning, this framework shows that identical Fe contents can yield different intermetallic ...
Jaemin Wang +2 more
wiley +1 more source
International Journal of Mathematical Combinatorics, Vol.7A [PDF]
, 2013 The International J.Mathematical Combinatorics (ISSN 1937-1055) is a fully refereed international journal, sponsored by the MADIS of Chinese Academy of Sciences and published in USA quarterly comprising 460 pages approx.
Mao, Linfan (Editor-in-Chief)
core +1 more source