Results 41 to 50 of about 4,059 (256)

Topology Optimisation of Structural Steel with Non-Penalisation SEMDOT: Optimisation, Physical Nonlinear Analysis, and Benchmarking

Applied Sciences, 2023
In this work, Non-penalisation Smooth-Edged Material Distribution for Optimising Topology (np-SEMDOT) algorithm was developed as an alternative to well-established Topology Optimisation (TO) methods based on the solid/void approach.
Tiago Ribeiro, Yun-Fei Fu, Luís Bernardo, Bernard Rolfe   +3 more
doaj   +1 more source

Topology optimisation of transient compressible flow

Engineering with Computers
We present the first formulation of topology optimisation for transient compressible flow. We discretise the equations with a discontinuous Galerkin method, due to its similarity to the popular finite volume method, and its capacity to model discontinuities in the flow.
Diego Hayashi Alonso, Patrick E. Farrell, Julio Romano Meneghini, Emílio Carlos Nelli Silva   +3 more
openaire   +2 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

DEVELOPMENT OF A METHOD OF ADDITIVE MANUFACTURING BY MATERIAL EXTRUSION ALONG THREE-DIMENSIONAL CURVES

South African Journal of Industrial Engineering, 2019
A method of additive manufacturing (AM) for the extrusion of material along three-dimensional curves is proposed as an alternative to conventional methods of layer-based AM for the manufacture of components designed using topology optimisation.
Kirkman, D. M. , van der Merwe, A. F. , Campbell, R. I.   +2 more
doaj   +1 more source

Simultaneous Design of the Host Structure and the Polarisation Profile of Piezoelectric Sensors Applied to Cylindrical Shell Structures

Mathematics, 2022
Piezoelectric actuators and sensors are applied in many fields in order to produce forces or displacements with the aim of sensing, manipulating or measurement, among other functions.
David Ruiz, Sergio Horta Muñoz, Reyes García-Contreras   +2 more
doaj   +1 more source

Design of adsorption systems by topology optimisation. [PDF]

, 2019
Adsorption is a retention mechanism of fluid molecules on solid surfaces and presents a wide range of applications, such as refrigeration, separation processes and fuel storage. This work describes the modelling of gas adsorption on porous media and presents an optimisation approach for the design of adsorption systems based on topology optimisation. A
openaire   +2 more sources

Topological invariance in whiteness optimisation

, 2021
Increasing the light scattering efficiency of nanostructured materials is becoming an active field of research both in fundamental science and commercial applications. In this context, the challenge is to use inexpensive organic materials that come with a lower refractive index than currently used mineral nanoparticles, which are under increased ...
Haataja, Johannes S., Jacucci, Gianni, Schertel, Lukas, Vignolini, Silvia   +3 more
openaire   +2 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Topology Optimisation: Increasing the Speed and Reliability of Design [PDF]

15th AIAA/ISSMO Multidisciplinary Analysis and Optimization Conference, 2014
In this paper, topology optimisation is applied to the design of the rear fuselage of an unmanned aerial vehicle (UAV). A comparison is drawn between the performance of a design created through evolutionary structural optimisation (ESO) and a baseline design modelled on a manually designed and successfully flow fuselage geometry, for different wing ...
Kelly, Liam, Keane, Andy J., Sobester, Andras, Toal, David J.J.   +3 more
openaire   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source