Results 51 to 60 of about 2,142,622 (300)

Topology optimization of turbulent flows [PDF]

Computer Methods in Applied Mechanics and Engineering, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Cetin B. Dilgen, Sumer B. Dilgen, David R. Fuhrman, Ole Sigmund, Boyan S. Lazarov   +4 more
openaire   +4 more sources

A geometry optimization framework for photonic crystal design [PDF]

, 2012
The performance of photonic crystal devices can depend strongly on their geometry. Alas, their fundamental physics offers relatively little by way of pointers in terms of optimum shapes, so numerical design search techniques must be used in an attempt to
Thomas, K.S., K. Djidjeli, K.S. Thomas, Sobester, A., E.E. Hart, S.J. Cox, Djidjeli, K., M. Molinari, Hart, E.E., Molinari, M., A. Sóbester, Cox, S.J.   +11 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Fatigue Life and Lightweight Design of Demolition Robot Rotary Joint Based on Topology Optimization

Machines
As a critical component of demolition robots, the rotary joint supports the entire manipulator arm and operates under severe loading conditions, rendering it highly susceptible to fatigue failure.
Chentao Yao, Wendi Dong, Xingtao Zhang, Xizhong Cui, Zhuangwei Niu, Zheng-Yang Li, Jianwei Zhao, Dongjia Yan, Hongbo Li   +8 more
doaj   +1 more source

Evolutionary approach for spatial architecture layout design enhanced by an agent-based topology finding system

Frontiers of Architectural Research, 2017
This paper presents a method for the automatic generation of a spatial architectural layout from a user-specified architectural program. The proposed approach binds a multi-agent topology finding system and an evolutionary optimization process.
Zifeng Guo, Biao Li
doaj   +1 more source

Topological Portfolio Selection and Optimization

4th ACM International Conference on AI in Finance, 2023
Modern portfolio optimization is centered around creating a low-risk portfolio with extensive asset diversification. Following the seminal work of Markowitz, optimal asset allocation can be computed using a constrained optimization model based on empirical covariance. However, covariance is typically estimated from historical lookback observations, and
Yuanrong Wang, Antonio Briola, Tomaso Aste   +2 more
openaire   +3 more sources

Minmax topology optimization [PDF]

, 2011
We describe a systematic approach for the robust optimal design of linear elastic structures subjected to unknown loading using minmax and topology optimization methods.
Brittain, Kevin
core  

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

TOPOLOGY OPTIMIZATION METHOD BASED ON SIMP-MMC FOR STRUCTURE SIZE PRECISE CONTROL

Jixie qiangdu, 2022
With the development of structural topology optimization methods, some scholars had proposed strategies to integrate existing topology optimization methods to improve the manufacturability of topology optimization result.
ZHANG JunFeng, LIAO JingYu, LIU EnHai
doaj