Results 31 to 40 of about 9,436 (304)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Topos y Dramaturgia

open access: yesPensamiento palabra y obra, 2013
“Topoi and dramaturgy”: analysis of the meanings and the expressive strategy in two symphonic movements of Bela Bartok (Two images Op. 10/ I “in full bloom” and the adagio of the Music for strings, percussion and celesta)
Marta Grabocz   +1 more
openaire   +3 more sources

Eu-topos / ou-topos: utopías y futuro

open access: yesOltreoceano, 2021
The aim of this study is to demonstrate how utopias reclaim a circumscribed microcosm that takes the contours of the island evoked by the canon of utopian writing. It also shows how they reactivate the dream of reaching eu-topos, the beautiful place which thus prevails over the concept of ou-topos, the place that does not exist.
openaire   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

Geographical component of the chronotope of the English scientific discourse and the forms of its representation

open access: yesВестник Самарского университета: История, педагогика, филология
The article deals with the geographical component of the chronotope of the English scientific discourse. The authors identify the forms of geographical representation of the chronotope of scientific discourse, determine the degree of identifiability of ...
S. A. Tserkovnov, K. B. Svoikin
doaj   +1 more source

Taming the Immiscibility of Gold, Iron, and Boron to Craft Chemodegradable Nanoparticles for Multimodal Imaging and Radiotherapy

open access: yesAdvanced Healthcare Materials, EarlyView.
Over half of cancer patients undergo radiotherapy. Laser ablation enabled the synthesis of immiscible Au‐Fe‐B nanoparticles designed as degradable bimodal radiosensitizers for X‐ray radiotherapy (XRT), boron neutron capture therapy (BNCT), and bimodal imaging for X‐ray computed tomography (CT) and magnetic resonance imaging (MRI). These nanosensitizers
Michael Bissoli   +15 more
wiley   +1 more source

Is Quantum Field Theory Necessarily “Quantum”?

open access: yesQuantum Reports
The mathematical universe of the quantum topos, which is formulated on the basis of classical Boolean snapshots, delivers a neo-realist description of quantum mechanics that preserves realism.
Ali Shojaei-Fard
doaj   +1 more source

Topological spaces versus frames in the topos of $M$-sets [PDF]

open access: yesCategories and General Algebraic Structures with Applications
In this paper we study topological spaces, frames, and their confrontation in the presheaf topos of $M$-sets for a monoid $M$. We introduce the internalization, of the frame of open subsets for topologies, and of topologies of points for frames, in our ...
Mojgan Mahmoudi, Amir H. Nejah
doaj   +1 more source

Biomimetic Copper Nanoparticles Coated with ACE2‐Overexpressing Membranes for Selective SARS‐CoV‐2 Neutralization and Disinfection

open access: yesAdvanced Healthcare Materials, EarlyView.
By fusing ACE2‐overexpressing membrane‐integrated liposome (MIL) with copper nanoparticles, the biomimetic Cu@MIL nanostructures were created that directly hijack the SARS‐CoV‐2 entry pathway. These particles combine potent virus‐targeting precision with intrinsic antiviral activity, achieving rapid neutralization and disinfection.
Pooja Aich   +8 more
wiley   +1 more source

„Z takimi patronami można iść na koniec świata”. Strategie retoryczne stosowane w crowdfundingu na wybranych przykładach z serwisu Patronite.pl

open access: yesRes Rhetorica, 2023
Celem niniejszego artykułu jest analiza strategii retorycznych w donacyjnym modelu crowdfundingu. Materiałem badawczym jest 40 wizytówek twórców w serwisie Patronite.pl, którzy prowadzą profile w kategorii publicystyka, zrzeszają co najmniej stu ...
Elżbieta Pawlak-Hejno
doaj   +1 more source

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