Results 81 to 90 of about 21,546 (268)

Sodium Ions Affect GPR17 Conformational States and Functionality

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Sodium is an allosteric modulator of several class‐A GPCR regulating active versus inactive conformation state and may be a critical issue for the optimization of crystallization procedures. Herein, the role of Na+ in the regulation of GPR17 conformational states was studied through MD simulations of GPR17 wild‐type and mutated on two ...
Luca Palazzolo   +6 more
wiley   +1 more source

El topos simbolista de la ciudad muerta en la tradición literaria europea y española

open access: yesRevista de Filología y Lingüística de la Universidad de Costa Rica, 2014
En este artículo se realiza un exhaustivo recorrido por la representación de la ciudad muerta en la literatura europea y española fin de siglo, con especial interés en Rodenbach, en el caso belga, y en Azorín, en el español.
Dorde Cuvardic García
doaj   +1 more source

EU-TOPOS / OU-TOPOS: UTOPÍAS Y FUTURO [Eu-topos / Ou-topos: Utopias and the Future]

open access: yes, 2021
The aim of this study is to demonstrate how utopias reclaim a circumscribed microcosm that takes the contours of the island evoked by the canon of utopian writing. It also shows how they reactivate the dream of reaching eutopos, the beautiful place which thus prevails over the concept of outopos, the place that does not exist.
openaire   +1 more source

A lysosome‐targeted ultra‐sensitive viscosity probe for monitoring viscosity alterations during chemotherapy

open access: yesSmart Molecules, EarlyView.
A novel chemosensing platform based on a molecular rotor architecture is established for specific, dynamic detection of lysosomal viscosity. The platform allows real‐time tracking of lysosomal viscosity fluctuations induced by various chemotherapeutic agents, highlighting its significant potential as a powerful tool for early cancer diagnostics and ...
Haoyang Song   +6 more
wiley   +1 more source

On the development of Slovak prose in the second half of the 20th century [PDF]

open access: yesSlovenska Literatura, 2008
The article “Remarks on Development of the Slovak 20th Century Prose” was made as a lecture and presented in the end of November 2002 in the Slavic Institute of Vienna University.
František Koli
doaj  

Climatic factors, landscape composition and host plant traits co‐drive fruit infestation of unmanaged walnut trees by the invasive pest fly Rhagoletis completa (Cresson, 1929) (Diptera: Tephritidae)

open access: yesAgricultural and Forest Entomology, EarlyView.
The study examined multiscale factors influencing walnut fruit infestations by the invasive pest fly Rhagoletis completa. Infestation rates increased with fruit size, host tree abundance, grasslands, hedgerows and temperatures, but decreased with anthropogenic habitats and heavy spring rainfall.
Méghan Boulembert   +5 more
wiley   +1 more source

The Modified Realizability Topos [PDF]

open access: yes, 1996
The modified realizability topos is the semantic (and higher order) counterpart of a variant of Kreisel's modified realizability (1957). These years, this realizability has been in the limelight again because of its possibilities for modelling type ...
Oosten, Jaap van
core  

Basic subtoposes of the effective topos

open access: yesAnnals of Pure and Applied Logic, 2013
We employ a new tool (sights) to investigate local operators in the Effective Topos. A number of new such local operators is analyzed using this machinery. Moreover, we investigate a local operator defined in the thesis of A. Pitts, and establish that its corresponding subtopos satisfies true arithmetic.
Sori Lee, Jaap van Oosten
openaire   +6 more sources

Male Mice Heterozygous for Protamine 1 and Protamine 2 Are Infertile, Displaying Sperm Damage and Retention of Protamine 2 Precursors, Transition Proteins, and Histones

open access: yesAndrology, EarlyView.
ABSTRACT Background During spermiogenesis, protamines (PRMs) replace histones to hypercondense and protect sperm DNA. Rodents and primates express two PRMs (PRM1 and PRM2). Alterations of species‐specific PRM ratios are associated with sub‐ or infertility in mice and humans.
Gina Esther Merges   +6 more
wiley   +1 more source

R. Bruni, Il divino entusiasmo dei poeti. Storia di un topos, Torino, Aragno, 2011

open access: yes, 2012
Una storia del topos dell'entusiasmo poetico da Platone al '900, passando per Dante, per il Rinascimento italiano e per il Romanticismo ...
NATALE, Massimo
core   +1 more source

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