Results 151 to 160 of about 32,008 (339)
topping-liftAn' then there's the main topping-lift which goes from the top o' the boom to the top o' the mast head, [an'] a block on the end of that and sheaves [?] in...into the gaff for liftin' the boom up or down.YesJ.D.A.
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We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Topping Ice Cream Business Plan
The brand Topping Ice Cream was established in the year 2013 May 18 without pervious planning or preparation. The urge of starting such business was initiated by two co-founders with the pure intension of providing a better product and with the right ...
Chang, Zei-Uei, 張詩瑀
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Description of the subject. In Mali, cotton (Gossypium hirsutum L.) plays an essential role in economic and social activities in terms of income generation, rural organization and modernization of production systems.
Amadou Traoré +7 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Spray-topping or pasture topping is the application of a sub-lethal rate of herbicide when grasses are coming into head and flowering. The aim is to reduce the production of viable seed and the seedling population in the following year.
Department of Primary Industries and Regional Development, Western Australia
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Patent for improvement to cotton-topping machine to make growth compactly, including instructions and ...
Palm, George William
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Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source

