Results 71 to 80 of about 33,208 (149)

Disulfide relays and phosphorylative cascades: Partners in redox-mediated signaling pathways [PDF]

open access: yes, 2005
Modifications of specific amino-acid residues of proteins are fundamental in order to modulate different signaling processes among which the cascade of phosphorylation represents the most effective example.
A Delaunay   +42 more
core   +1 more source

Defining the clinical role of the mammalian target of rapamycin (mTOR) in lung cancer

open access: yes, 2010
Lung cancer is the biggest cancer killer. Most patients present with advanced disease. These diseases are not amenable to surgery which currently provides the best chance of cure.
Dhillon, Perminder Tony Singh   +1 more
core   +1 more source

Atypical protein kinase C (PKCzeta/lambda) is a convergent downstream target of the insulin-stimulated phosphatidylinositol 3-kinase and TC10 signaling pathways. [PDF]

open access: yes, 2004
Insulin stimulation of adipocytes resulted in the recruitment of atypical PKC (PKCzeta/lambda) to plasma membrane lipid raft microdomains. This redistribution of PKCzeta/lambda was prevented by Clostridium difficile toxin B and by cholesterol depletion ...
Hwang, Joseph B   +4 more
core   +1 more source

Abstracts

open access: yes
Cancer Science, Volume 117, Issue S1, Page 1-2148, January 2026.
wiley   +1 more source

Editorial: Determinants of Cell Size

open access: yesFrontiers in Cell and Developmental Biology, 2017
Mikael Björklund   +2 more
doaj   +1 more source

Regulation of nicotinic acetylcholine receptors by tyrosine kinases in the peripheral and central nervous system: same players, different roles [PDF]

open access: yes, 2018
.: Nicotinic acetylcholine receptors (nAChRs) exist in many subtypes and are found in the peripheral and central nervous system where they mediate or modulate synaptic transmission.
Fuhrer, C., Wiesner, A.
core  

Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB1 Signaling Axis. [PDF]

open access: yes, 2017
Autophagy activated after DNA damage or other stresses mitigates cellular damage by removing damaged proteins, lipids, and organelles. Activation of the master metabolic kinase AMPK enhances autophagy. Here we report that cyclin D1 restrains autophagy by
Bisetto, Sara   +17 more
core   +1 more source

Characterization of Mast2 kinase defines structural features, regulation, and substrates. [PDF]

open access: yesJ Biol Chem
Lemke MC   +15 more
europepmc   +1 more source

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