Disulfide relays and phosphorylative cascades: Partners in redox-mediated signaling pathways [PDF]
Modifications of specific amino-acid residues of proteins are fundamental in order to modulate different signaling processes among which the cascade of phosphorylation represents the most effective example.
A Delaunay +42 more
core +1 more source
Defining the clinical role of the mammalian target of rapamycin (mTOR) in lung cancer
Lung cancer is the biggest cancer killer. Most patients present with advanced disease. These diseases are not amenable to surgery which currently provides the best chance of cure.
Dhillon, Perminder Tony Singh +1 more
core +1 more source
Atypical protein kinase C (PKCzeta/lambda) is a convergent downstream target of the insulin-stimulated phosphatidylinositol 3-kinase and TC10 signaling pathways. [PDF]
Insulin stimulation of adipocytes resulted in the recruitment of atypical PKC (PKCzeta/lambda) to plasma membrane lipid raft microdomains. This redistribution of PKCzeta/lambda was prevented by Clostridium difficile toxin B and by cholesterol depletion ...
Hwang, Joseph B +4 more
core +1 more source
Editorial: Determinants of Cell Size
Mikael Björklund +2 more
doaj +1 more source
Regulation of nicotinic acetylcholine receptors by tyrosine kinases in the peripheral and central nervous system: same players, different roles [PDF]
.: Nicotinic acetylcholine receptors (nAChRs) exist in many subtypes and are found in the peripheral and central nervous system where they mediate or modulate synaptic transmission.
Fuhrer, C., Wiesner, A.
core
Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB1 Signaling Axis. [PDF]
Autophagy activated after DNA damage or other stresses mitigates cellular damage by removing damaged proteins, lipids, and organelles. Activation of the master metabolic kinase AMPK enhances autophagy. Here we report that cyclin D1 restrains autophagy by
Bisetto, Sara +17 more
core +1 more source
[Expression of Concern] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway. [PDF]
Meng HY +6 more
europepmc +1 more source
Integrative Multi-Omics Analyses Reveal the Global Regulation Network of the Microalga <i>Nannochloropsis oceanica</i> Under Nitrogen Stress Adaptation. [PDF]
You W, Xu C, Zhang J, Poetsch A.
europepmc +1 more source
Characterization of Mast2 kinase defines structural features, regulation, and substrates. [PDF]
Lemke MC +15 more
europepmc +1 more source

