Results 51 to 60 of about 20,110 (149)

MITOGEN‐ACTIVATED PROTEIN KINASE9 fine‐tunes hypoxia signaling by phosphorylating ERF‐VII transcription factors in Arabidopsis

New Phytologist, Volume 250, Issue 2, Page 1023-1040, April 2026.
Summary In plants, hypoxia sensing is controlled by the stabilization of group VII ethylene response factors (ERF‐VIIs), which are post‐translationally activated by the mitogen‐activated protein kinases (MAPKs) MPK3 and MPK6. However, how plants fine‐tune the MPK3/MPK6‐mediated phosphorylation of ERF‐VIIs to maintain cellular homeostasis remains ...
De‐Mian Zhou, Ying Zhou, Xu‐Chen Wu, Qing‐Ying Ke, Tian‐Yi Zhang, Zi‐Yuan Yin, Li‐Li Shi, Ke Liao, Shi Xiao, Qin‐Fang Chen   +9 more
wiley   +1 more source

Cross-talk and specificity of signal perception and transduction in response to salt and drought stress in B. napus.

, 2015
The most differentially expressed signaling-related proteins were integrated and marked in red (up-regulated) or green (down-regulated). The blue region in the middle represented the cross-talk pathway shared by both the salt and drought responses.
Jun Li (6494), Xiaojue Peng (810946), Xiaohong Yan (176496), Junling Luo (810945), Shaohua Tang (40619), Xiaofei Li (334285), Xinhua Zeng (496861), Gang Wu (23885)   +7 more
core   +1 more source

Biomarkers for the estimation of isoproterenol‐induced myocardial infarction: A review of key parameters

Journal of Intelligent Medicine, Volume 3, Issue 1, Page 47-68, March 2026.
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran, Tarique Mahmood, Farogh Ahsan, Shahzadi Bano, Vaseem Ahamad Ansari, Mohd Adnan   +5 more
wiley   +1 more source

Review of Amino Acid Foliar Application as a Stress Mitigation Strategy: Unraveling the Protective Mechanisms Against Abiotic Stress

Journal of Sustainable Agriculture and Environment, Volume 5, Issue 1, March 2026.
ABSTRACT The foliar application of amino acids offers a promising strategy to mitigate multiple abiotic stresses—drought, salinity, heat and heavy metals—by enhancing plant physiological, biochemical and molecular responses. This review synthesises recent advances in understanding how external amino acids function as bio‐stimulants, focusing on ...
Xiaoyu Ma, Mirezhatijiang Kayoumu, Yue Yin, Zewen Wang, Guilan Duan   +4 more
wiley   +1 more source

Enzymatic and biochemical characterization of the Target Of Rapamycin (TOR) signaling pathway

, 2011
Target Of Rapamycin (TOR) is a master regulator of cell growth in eukaryotes. TOR is a large, highly conserved serine/threonine protein kinase that belongs to the family of phosphatidylinositol-3-kinase-related kinases (PIKKs).
Lempiainen, Aino
core   +1 more source

A novel nuclear function for the centrosomal serine/threonine kinase Nek2 [PDF]

, 2010
Numerose chinasi che regolano il ciclo centrosomale sono frequentemente regolate in maniera aberrante nelle cellule neoplastiche. Cambiamenti nella loro espressione possono portare ad alterazioni nella duplicazione del centrosoma quindi aneuploide.
Barbagallo, Federica, Barbagallo, F
core   +1 more source

VIA DE SINALIZAÇÃO MTOR COMO GÊNESE DA EPILEPSIA: UMA REVISÃO DE LITERATURA

, 2023
INTRODUÇÃO: A epilepsia é uma doença neurológica que afeta quase 3% da população mundial, ocasionando uma predisposição contínua a ocorrência de crises epilépticas, o que gera consequências cognitivas, psicológicas e sociais para esses indivíduos que são
Luis Portela Pires, Hugo Araújo Salis, Jefferson de Araújo Galeno, Watina Rodrigues Dias, Dalilla Viana Moreira, Sebastião Danilo Vaz do Rêgo, Larruama Soares Figueiredo, Thayná Grasielly de Campos Melo Santos Rodrigues, Nathália Castelo Branco Vieira Miranda de Carvalho, Jercy Gabriella Gomes Marinho, Karen Natany Costa de Oliveira, Brenda de Moura Meneses, Fernando José de Morais Silva, Andressa Amorim dos Santos   +13 more
core   +1 more source

The role of raptor during brain development and in adult forebrain neurons [PDF]

, 2012
mTOR is a serine/threonine protein kinase that appears in two functionally distinct multi-protein complexes. mTOR together with the scaffold protein raptor forms mTOR complex1 (mTORC1) that is inhibited in its function by rapamycin.
Lustenberger, Regula Maria
core   +1 more source

Regulation of autophagy‐mediated pathways by diet, physical activity, and sleep in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract Alzheimer's disease (AD) is a progressive, age‐related, neurodegenerative disorder marked by cognitive decline, memory loss, and accumulation of amyloid beta (Aβ) plaques and tau tangles. A key feature of AD is impaired protein homeostasis, often driven by autophagy dysfunction.
Ajish Ariyath, Zoe Mputhia, Christopher Dougherty, Bushra Kaleelur Rahuman, W. M. A. D. Binosha Fernando, Belinda Brown, Samantha L. Gardener, Stephanie R. Rainey‐Smith, Ralph Martins, Prashant Bharadwaj   +9 more
wiley   +1 more source

Calorie Restriction Effects on Aging, Learning Performance, and Transcription in Aged Aplysia californica

Genes, Brain and Behavior, Volume 25, Issue 1, February 2026.
Buccal ganglia inter‐ and motoneuronal transcriptional changes were investigated after learning food is inedible (LFI) in Aplysia californica reared on different diets at two ages. Those reared on calorie restriction showed delayed signs of aging and maintained their performance in LFI when aged while those reared on ad‐lib did not. ABSTRACT Along with
Eric C. Randolph, Lynne A. Fieber
wiley   +1 more source