Results 51 to 60 of about 33,208 (149)

Calorie Restriction Effects on Aging, Learning Performance, and Transcription in Aged Aplysia californica

Genes, Brain and Behavior, Volume 25, Issue 1, February 2026.
Buccal ganglia inter‐ and motoneuronal transcriptional changes were investigated after learning food is inedible (LFI) in Aplysia californica reared on different diets at two ages. Those reared on calorie restriction showed delayed signs of aging and maintained their performance in LFI when aged while those reared on ad‐lib did not. ABSTRACT Along with
Eric C. Randolph, Lynne A. Fieber
wiley   +1 more source

Quantitative phosphoproteomics of cytotoxic T cells to reveal Protein Kinase D 2 regulated networks [PDF]

, 2014
The focus of the present study was to characterize the phosphoproteome of cytotoxic T cells and to explore the role of the serine threonine kinase PKD2 (Protein Kinase D2) in the phosphorylation networks of this key lymphocyte population.
Azzam, Balagopalan, Beadling, Caenepeel, Chiang, Cornish, Cox, Cox, Dequiedt, Doreen A. Cantrell, Döppler, Eggers, Eiseler, Eiseler, Flotho, Franz-Wachtel, Fugmann, Grønborg, Hao, Hardie, Hausser, Hay, Huang, Hunter, Hutti, Huttlin, Jens L. Hukelmann, Juergen Goebel, Kajiho, Kalia, Kitao, Komander, Larghi, Malek, Marklund, María N. Navarro, Matthews, Matthews, Matthews, Mayya, Navarro, Navarro, Ng, Nhek, Nishikawa, Olayioye, Parra, Parra, Peterburs, Pipkin, Rey, Rozengurt, Ruperez, Seaman, Sinclair, Soares, Spitaler, Spratley, Tamas, Urso, Vizcaíno, Wang, Wang, Waugh, Weninger, Wood, Zarrouk, Zhou, Ziegler   +68 more
core   +3 more sources

A structural perspective on α‐glucan catabolism in oxygenic phototrophs

The Plant Journal, Volume 125, Issue 3, February 2026.
SUMMARY Starch and glycogen are the main α‐glucan storage polymers in oxygenic photoautotrophs, ensuring metabolic continuity during day/night cycles and environmental stress. Their mobilization requires a suite of catabolic enzymes whose activities are tightly regulated to balance carbon storage with energy demands.
Sofia Doello, Dmitry Shvarev
wiley   +1 more source

SNRK3.15 Is a Crucial Component of the Sulfur Deprivation Response in Arabidopsis thaliana

Plant Direct, Volume 10, Issue 1, January 2026.
ABSTRACT Sulfate deprivation (–S) results in numerous metabolic and phenotypic alterations in plants. Kinases are often key players in transducing nutrient status signals to molecular components involved in metabolic and developmental program regulation, but despite the physiological importance of sulfur, to date, no signaling kinases have been ...
Anastasia Apodiakou, Elmien Heyneke, Saleh Alseekh, Pinnapat Pinsorn, Sabine Metzger, Stanislav Kopriva, Waltraud Schulze, Rainer Hoefgen, Sarah J. Whitcomb   +8 more
wiley   +1 more source

Microbial carcinogenic toxins and dietary anti-cancer protectants [PDF]

, 2017
Several toxins are known which account for the ability of some bacteria to initiate or promote carcinogenesis. These ideas are summarised and evidence is discussed for more specific mechanisms involving chymotrypsin and the bacterial chymotryptic enzyme ...
Darlington, L. Gail, Stone, Trevor W.
core   +2 more sources

Epigenetic Age Prediction Using N6‐Methyladenine in the Buff‐Tailed Bumblebee (Bombus terrestris)

Aging Cell, Volume 25, Issue 1, January 2026.
In bumblebees, age‐related patterns of N6‐methyladenine can be used to build accurate epigenetic clocks that are responsive to lifespan‐extending interventions, providing the first proof of concept that this epigenetic mark can be used as a biomarker of aging.
Thibaut Renard, Morgane Boseret, Serge Aron   +2 more
wiley   +1 more source

The mTOR Pathway in Breast Cancer [PDF]

, 2018
There is currently a wealth of information regarding the mutations that contribute to cancer development. Most of these mutations alter the expression and activity of signal transduction proteins.
Boulay, Anne, Hynes, Nancy
core  

The chloroplast import receptor Toc34 functions as preprotein-regulated GTPase [PDF]

, 2002
Toc34 is a protein of the chloroplast outer envelope membrane that acts as receptor for preproteins containing a transit sequence. The recognition of preproteins by Toc34 is regulated by GTP binding and phosphorylation.
Hörth, P., Jelic, M., Motzkus, M., Schleiff, E., Soll, J., Sveshnikova, N.   +5 more
core   +1 more source

Regulator of G‐Protein Signalling Protein AaRgs2 Negatively Regulates Appressorium‐Like Formation of Alternaria alternata Induced by Pear Cutin Monomer via the AaRgs2‐AaGα1‐AaAC Module

Molecular Plant Pathology, Volume 27, Issue 1, January 2026.
AaRgs2 negatively regulates appressorium‐like formation of A. alternata induced by pear cutin monomer via the AaRgs2‐AaGα1‐AaAC module. ABSTRACT Pathogenic fungi have developed complex and specific infection strategies to invade host tissues successfully.
Miao Zhang, Yuanping Nan, Yongcai Li, Yang Bi, Dov B. Prusky   +4 more
wiley   +1 more source

Guanine nucleotide exchange factor αPIX leads to activation of the Rac 1 GTPase/glycogen phosphorylase pathway in interleukin (IL)-2-stimulated T cells [PDF]

, 2015
Recently, we have reported that the active form of Rac 1 GTPase binds to the glycogen phosphorylase muscle isoform (PYGM) and modulates its enzymatic activity leading to T cell proliferation.
Gálvez, Patricia, Lacerda, Hadriano M, Llavero, Francisco, Osinalde, Nerea, Parada, Luis A, Urzelai, Bakarne, Zugaza, José L   +6 more
core   +2 more sources