Results 41 to 50 of about 332,444 (133)

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Metabolic Atlas and Multi‐Omics Analysis of Maize Pericarp: Coordinated Regulatory Mechanism of Morphogenesis and Flavonoid Metabolism

Food and Energy Security, Volume 15, Issue 3, May/June 2026.
ABSTRACT The maize pericarp serves not only as a physical protective barrier of the seed but also as a critical functional interface involved in environmental response and physiological regulation. Systematic analysis of the metabolic basis of nutritional components and related metabolites in the maize pericarp is of great importance for quality ...
Yanru Wang, Qingmei Men, Shuang Wang, Minkun Guo, Anran Song, Chuanyu Wang, Yanxin Zhao, Guanmin Huang, Peng Man, Ying Zhang, Xinyu Guo   +10 more
wiley   +1 more source

The coordination of T-cell function by serine/threonine kinases

, 2010
The function of T-lymphocytes during adaptive immune responses is directed by antigen receptors, costimulatory molecules, and cytokines. These extrinsic stimuli are coupled to a network of serine/threonine kinases that control the epigenetic ...
Cantrell, Doreen, Finlay, David, D. Finlay, D. Cantrell   +3 more
core   +1 more source

The TriTryp Phosphatome: analysis of the protein phosphatase catalytic domains [PDF]

, 2007
Background The genomes of the three parasitic protozoa Trypanosoma cruzi, Trypanosoma brucei and Leishmania major are the main subject of this study. These parasites are responsible for devastating human diseases known as Chagas disease, African sleeping
Szoor, Balazs; id_orcid, Brenchley Rachel, Matthews Keith, Balázs Szöőr, Stevens Robert, Tabernero, Lydia, McElhinney Helen, Tabernero, Lydia; id_orcid, McElhinney, Helen, Huxley-Jones, Julie, Julie Huxley-Jones, Brenchley, Rachel, Tariq, Humera, Helen McElhinney, Tariq Humera, Keith Matthews, Matthews, Keith; id_orcid, Rachel Brenchley, Szöőr Balázs, Robert Stevens, Tabernero Lydia, Szöor, Balázs, Humera Tariq, Lydia Tabernero, Huxley-Jones Julie, Stevens, Robert, Matthews, Keith   +26 more
core   +1 more source

Inferring Gene Regulatory Network Architecture Underlying Complex Traits: An Integrative Analysis of Mutant Lifespan and Gene Expression Profiles Identifies Master Regulators and Key Functional Modules for Yeast Aging

Aging Cell, Volume 25, Issue 5, May 2026.
We developed a LASSO‐based approach to uncover a three‐layered “fan‐in fan‐out” network architecture for complex traits like yeast aging, showing that peripheral genes influence lifespan indirectly through master regulators, which converge on core functional modules (e.g., stress response, autophagy).
Meng Ma, Juan Long, Yuting Chen, Yanqiu Shao, Man Zhu, Jiashun Zheng, Lu Yang, Yin Xiao, Matt Kaeberlein, Brian K. Kennedy, Yi Zheng, Hao Li, Jing Yang   +12 more
wiley   +1 more source

Impact of Serine/Threonine Protein Kinases on the Regulation of Sporulation in Bacillus subtilis. [PDF]

, 2016
Bacteria possess many kinases that catalyze phosphorylation of proteins on diverse amino acids including arginine, cysteine, histidine, aspartate, serine, threonine and tyrosine.
Elodie Foulquier, Anne Galinier, Anne eGalinier, Galinier, Anne, Pompeo, Frederique, Frédérique ePompeo, Elodie eFoulquier, Foulquier, Elodie, Frédérique Pompeo   +8 more
core   +1 more source

Protein-serine/threonine/tyrosine kinases in bacterial signaling and regulation

, 2013
In this review, we address some recent developments in the field of bacterial protein phosphorylation, focusing specifically on serine/threonine and tyrosine kinases. We present an overview of recent studies outlining the scope of physiological processes
Yves Pagot, Cousin, C., Shi, Lei, L., Mijakovic, Ivan, Poncet, S., Cousin, Charlotte, C., Abderahmane Derouiche, Lei Shi, Mijakovic, Ivan, I., Derouiche, Abderahmane, A., Pagot, Yves, Y., Shi, L., Pagot, Y., Charlotte Cousin, Derouiche, A., Poncet-Mouturat, Sandrine, S., Ivan Mijakovic, Sandrine Poncet   +17 more
core   +1 more source

Serine/threonine protein kinases and apoptosis

, 2000
Over the past decade, our understanding of apoptosis, or programmed cell death, has increased greatly, with the identification of some of the major components of the apoptotic programme and the processes regulating their activation. Although apoptosis is
Deacon, E, Lord, Janet; id_orcid, Henriquez, Nico, Scheel-Toellner, Dagmar; id_orcid, Salmon, Michael, Cross, TG   +5 more
core   +1 more source

Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells [PDF]

, 2014
The insulin/IGF-1 (insulin-like growth factor 1)-activated protein kinase Akt (also known as protein kinase B) phosphorylates Ser487 in the ‘ST loop’ (serine/threonine-rich loop) within the C-terminal domain of AMPK-a1 (AMP-activated protein kinase-a1 ...
Leslie, Nicholas R., Leslie, Nicholas R.; id_orcid, Ross, Fiona A., Hardie, D. Grahame, Tibarewal, Priyanka, Gowans, Graeme J., Hawley, Simon A.   +6 more
core   +1 more source

Type II receptor serine/threonine kinases in GtoPdb v.2025.3 [PDF]

Type II protein receptor serine/threonine kinases interact with transforming growth factor beta (TGFβ), bone morphogenic protein (BMP) or MÀllerian inhibiting substrate (MIS).
Peach, Chloe J.
core   +1 more source