Results 21 to 30 of about 33,208 (149)

Over-expression of an S-domain receptor-like kinase extracellular domain improves panicle architecture and grain yield in rice. [PDF]

, 2015
The S-domain receptor kinase (SRK) comprises a highly polymorphic subfamily of receptor-like kinases (RLKs) originally found to be involved in the self-incompatibility response in Brassica.
Li, Hongyu, Lin, Chentao, Liu, Bin, Liu, Jun, Qin, Zhengrui, Zhang, Chengsheng, Zhang, Chunyu, Zhao, Tao, Zou, Xiaohua   +8 more
core   +2 more sources

Sugar metabolism and the plant Target Of Rapamycin kinase: a sweet operaTOR?

Frontiers in Plant Science, 2013
In eukaryotes, the ubiquitous TOR (Target Of Rapamycin) kinase complexes have emerged as central regulators of cell growth and metabolism. The plant TOR complex 1 (TORC1), that contains evolutionary conserved protein partners, has been shown to be ...
Thomas eDobrenel, Chloé eMarchive, Marianne eAzzopardi, Gilles eClément, Manon eMoreau, Rodnay eSormani, Christophe eRobaglia, Christian eMeyer   +7 more
doaj   +1 more source

11 beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle [PDF]

, 2009
OBJECTIVE: Glucocorticoid excess is characterized by increased adiposity, skeletal myopathy, and insulin resistance, but the precise molecular mechanisms are unknown.
A. Yu, Abdallah, Aguirre, Araki, C. Lenaghan, D. Laber, D. M. Smith, Danielsson, Djurhuus, Draznin, Fraser, G. Convey, G. G. Lavery, Geraghty, Giorgino, Giorgino, Giorgino, Hanada, I. J. Bujalska, J. K. Sethi, J. W. Tomlinson, Jang, K. Hegyi, Kido, Kim, L. L. Gathercole, Larsson, Liu, M. Sherlock, M  ssig, P. M. Stewart, R. Mayers, S. A. Morgan, Saad, van Staa, Watson, Whorwood, Zhang   +37 more
core   +3 more sources

Modulation of plant growth in vivo and identification of kinase substrates using an analog-sensitive variant of CYCLIN-DEPENDENT KINASE A;1 [PDF]

, 2016
BACKGROUND: Modulation of protein activity by phosphorylation through kinases and subsequent de-phosphorylation by phosphatases is one of the most prominent cellular control mechanisms.
Dissmeyer, N., Hammann, P., Harashima, H., Kramer, K., Nakagami, H., Nomura, Y., Schnittger, A.   +6 more
core   +2 more sources

Citron binds to PSD-95 at glutamatergic synapses on inhibitory neurons in the hippocampus [PDF]

, 1999
Synaptic NMDA-type glutamate receptors are anchored to the second of three PDZ (PSD-95/Discs large/ZO-1) domains in the postsynaptic density (PSD) protein PSD-95.
Apperson, Michelle, Kennedy, Mary B., Vazquez, Luis, Zhang, Wandong   +3 more
core   +1 more source

mTOR modulates CD8+ T cell differentiation in mice with invasive pulmonary aspergillosis

Open Life Sciences, 2018
CD8+ T cells are a vital component of the adaptive immune system and important for eliminating intracellular pathogens. Notably, mTOR activity is associated with CD8+ T effector memory (Tem) cell differentiation in fungal infections.
Wang Hao, Xiao Yu, Su Longxiang, Cui Na, Liu Dawei   +4 more
doaj   +1 more source

A constitutive active MAPK/ERK pathway due to BRAFV600E positively regulates AHR pathway in PTC [PDF]

, 2015
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor mediating the toxicity and tumor-promoting properties of dioxin. AHR has been reported to be overexpressed and constitutively active in a variety of solid tumors, but few data
Barollo, Susi, Bertazza, Loris, Bisognin, Andrea, Bortoluzzi, Stefania, Boscaro, Marco, Ceccato, Filippo, Ciato, Denis, Galuppini, Francesca, Guzzardo, Vincenza, Jaffrain Rea, Marie Lise, Mian, Caterina, Occhi, Gianluca, Pennelli, Gianmaria, Regazzo, Daniela, Scaroni, Carla, Vianello, Federica, WATUTANTRIGE FERNANDO, Sara   +16 more
core   +4 more sources

Essential and checkpoint functions of budding yeast ATM and ATR during meiotic prophase are facilitated by differential phosphorylation of a meiotic adaptor protein, Hop1 [PDF]

, 2015
A hallmark of the conserved ATM/ATR signalling is its ability to mediate a wide range of functions utilizing only a limited number of adaptors and effector kinases.
A Alcasabas, A Emili, A Traven, AA Ali, Alastair S. Goldman, Ana Penedos, Anthony L. Johnson, B Argunhan, C Chuang, D Bishop, D Durocher, D Durocher, D Lydall, D Ontoso, D Woltering, DK Bishop, Emily Strong, H Cartagena-Lirola, H Lee, H Niu, H Niu, H Tsubouchi, HY Wu, I Acosta, J Falk, J Harper, J Melo, JA Carballo, JA Carballo, JA Carballo, Jesús A. Carballo, JM Bailis, JP Lao, K Hofmann, L Wan, L Xu, M Shinohara, MB Yaffe, Michael Lichten, NM Hollingsworth, NM Hollingsworth, R Suhandynata, Rita S. Cha, RS Cha, S Gray, T Allers, T de los Santos, T Tougan, T Usui, V Busygina, Y Sanchez, YH Lo   +51 more
core   +11 more sources

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18:Catalytic receptors [PDF]

, 2017
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and ...
,, Alexander, Stephen Ph, Davies, Jamie A, Fabbro, Doriano, Faccenda, Elena, Harding, Simon D, Kelly, Eamonn, Marrion, Neil V, Pawson, Adam J, Peters, John A, Sharman, Joanna L, Southan, Christopher   +11 more
core   +5 more sources

Investigating the effect of target of rapamycin kinase inhibition on the Chlamydomonas reinhardtii phosphoproteome: from known homologs to new targets [PDF]

, 2019
Recuperado de: https://www.biorxiv.org/content/10.1101/310102v1Target of rapamycin (TOR) kinase is a conserved regulator of cell growth whose activity is modulated in response to nutrients, energy and stress.
Couso Liáñez, Inmaculada Concepción, Crespo González, José Luis, Hicks, Leslie, McConnell, Evan W., Perrine, Zoee, Umen, James G., Werth, Emily G.   +6 more
core   +1 more source