Results 31 to 40 of about 40,778 (214)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Stochastic Track Model for Tornado Risk Assessment in the U.S.

Frontiers in Built Environment, 2019
This paper presents the development of a stochastic tornado simulation model for the United States (US). The continental of the US is subjected to more than 1,000 tornadoes each year, causing significant financial losses and social disruption.
Fanfu Fan, Weichiang Pang
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

ERA5‐Based Convective Environments Favorable for Tornadoes in Southern China

Geophysical Research Letters
Tornado occurrences vary significantly across regions in the globe, attributable in part to variations in regional climate and topography. This study analyzes the long‐term convective environments associated with tornadoes in southern China, a region ...
Kanglong Cai, Lanqiang Bai, Qian Liu, Guixing Chen, Zeyu Zhang, Wenxiu Zhong   +5 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Xenia tornado damage photographs

, 1974
This is an aerial photograph of two homes destroyed after the 1974 tornado. On April 3, 1974, an F5 category tornado struck Xenia, Ohio. The tornado that struck Xenia was just one of at least 148 tornados that occurred in the South and Midwest in a ...
Ohio Department of the Adjutant General
core   +1 more source

Multimetrics Assessment of Explicit Hail Size Prediction Using Two- and Three-Moment Microphysical Schemes for a Severe Hailstorm in Northeastern China

Advances in Meteorology
At midnight on September 30, 2021, a severe hailstorm swept over northeastern China, producing egg-sized hail over Dalian Airport, causing damages to more than 40 aircrafts and imposing tremendous pressure on operational capacity of the airport.
Liping Luo, Yi Zhang, Xin Xu, Lin Deng, Yuehan Zhang, Zeyong Guo   +5 more
doaj   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

Tornado de fogo

, 2016
O recurso recria um tornado de fogo, baseado na conservação do momento angularEnsino Médio::FísicaEducação Superior::Ciências Exatas e da Terra ...
Fantini, Leandro
core   +1 more source