Results 41 to 50 of about 320,551 (292)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Parametric Wind Velocity Vector Estimation Method for Single Doppler LIDAR Model [PDF]
, 2017 Doppler lidar (LIght Detection And Ranging) can provide accurate wind velocity vector estimates by processing the time delay and Doppler spectrum of received signals.
Fang SHANG +5 more
core +2 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
A tornado daily impacts simulator for the central and southern United States
Meteorological Applications, 2020 In an average year (1979–2016), the United States experiences nearly 1,100 tornadoes, which cause a total of 68 fatalities. Annual fatality rates have decreased since the peak in the 1920s, but there is a concern that they could start to rise again with ...
Joshua J. Hatzis +2 more
doaj +1 more source
Selection of a Realistic Viscous Vortex Tangential Velocity Profile for Computer Simulation of Vortex-Structure Interaction [PDF]
, 2015 Structure loading by vortices is a relevant phenomenon in numerous fields of engineering significance. Computer modelling is a powerful tool that can be used to study the loading produced on structures by impacting vortices.
Selvam, R. P., Strasser, M. N.
core +3 more sources
Association of Corticospinal Tract Asymmetry With Ambulatory Ability After Intracerebral Hemorrhage
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Ambulatory ability after intracerebral hemorrhage (ICH) is important to patients. We tested whether asymmetry between ipsi‐ and contra‐lesional corticospinal tracts (CSTs) assessed by diffusion tensor imaging (DTI) is associated with post‐ICH ambulation.
Yasmin N. Aziz +25 more
wiley +1 more source
Atmosphere, 2019 This study demonstrates the capability of a cloud model in simulating a real-world tornado using observed radiosonde data that define a homogeneous background. A reasonable simulation of a tornado event in Beijing, China, on 21 July 2012 is obtained. The
Dan Yao, Zhiyong Meng, Ming Xue
doaj +1 more source
Statistical Models for Tornado Climatology: Long and Short-Term Views
, 2016 This paper estimates local tornado risk from records of past events using statistical models. First, a spatial model is fit to the tornado counts aggregated in counties with terms that control for changes in observational practices over time.
Elsner, James B. +2 more
core +1 more source
Recipe for Disaster: How the Dynamic Ingredients of Risk and Exposure Are Changing the Tornado Disaster Landscape [PDF]
, 2016 Tornado disasters and their potential are a product of both hazard risk and underlying physical and social vulnerabilities. This investigation appraises exposure, which is an important component and driver of vulnerability, and its interrelationship with
Ashley, Walker S., Strader, Stephen M.
core +2 more sources