Results 41 to 50 of about 2,227 (211)

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić   +4 more
wiley   +1 more source

Extended U.S. Tornado Outbreak During Late May 2019: A Forecast of Opportunity

open access: yesGeophysical Research Letters, 2019
The second half of May 2019 was an unusually active period for tornadic thunderstorms across the U.S. Great Plains, Midwest, and lower Great Lakes. While this period typically coincides with the peak climatological frequency of tornadoes, preliminary ...
Vittorio A. Gensini   +3 more
doaj   +1 more source

Navigating Storms: Examining Vultures’ Behavior in Response to Extreme Weather Events

open access: yesDiversity, 2023
Extreme weather events such as hurricanes and tornadoes have been found to change the spatial and temporal abundance of raptors by decreasing survival and forcing the emigration of individuals, or by increasing habitat heterogeneity and facilitating ...
Adrián Naveda-Rodríguez, Scott A. Rush
doaj   +1 more source

Development of Raman Spectroscopy and Machine Learning Methods for Protein Aggregate Quantification: Application to BSA in Chromatographic Processes

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Protein aggregation poses a significant risk to biopharmaceutical product quality, as even minor amounts of oligomeric species can compromise efficacy and safety. Rapid and reliable detection of protein aggregates thus remains a major challenge in biopharmaceutical manufacturing.
Jakob Heyer‐Müller   +4 more
wiley   +1 more source

Climate Change Risks and Customer Concentration: Evidence From US‐Listed Firms

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT While prior studies have investigated climate risks in supply chains, customer ESG pressures, and shared climate exposure, this paper is, to the best of our knowledge, the first to provide direct empirical evidence on the relationship between climate change risks and firms' customer concentration.
Thi Thuy Trang Nguyen   +2 more
wiley   +1 more source

Quality‐adjusted life years in the presence and absence of organized mammographic screening using data from BreastScreen Norway

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Although mammographic screening can reduce breast cancer mortality and extend life, some studies have found a negative impact on net quality‐adjusted life years (QALYs). Here, the authors estimated net QALYs associated with biennial mammographic screening for women aged 50–69 years in Norway under various scenarios.
Rick Groeneweg   +5 more
wiley   +1 more source

Understanding Autistic Young Adults' Perceptions and Experiences of Traumatic and Stressful Events

open access: yesJournal of Clinical Psychology, Volume 81, Issue 6, Page 445-461, June 2025.
ABSTRACT Objectives The aim of this study was to explore how young autistic adults experience and respond to stressful life events, and the relationship between autistic characteristics and symptoms of stress associated with these events. Methods Using an exploratory sequential mixed‐methods approach, an online qualitative survey was first administered
Alliyza Lim, Robyn L. Young
wiley   +1 more source

Damage Analysis of Three Long-Track Tornadoes Using High-Resolution Satellite Imagery

open access: yesAtmosphere, 2020
Remote sensing of tornado damage can provide valuable observations for post-event surveys and reconstructions. The tornadoes of 3 March 2019 in the southeastern United States are an ideal opportunity to relate high-resolution satellite imagery of damage ...
Daniel Burow   +2 more
doaj   +1 more source

Decision Threshold Setting in Binary Classification Problems—A Behavioral Lens

open access: yesJournal of Operations Management, EarlyView.
ABSTRACT When binary classification models are wrong, managers face misclassification costs. Although false positive outcomes imply unnecessary mitigation efforts, false negative outcomes imply overlooking the class of interest. Humans calibrate these ai models supporting operational systems by adjusting the decision threshold that translates ...
Patrick Moder, Kai Hoberg, Felix Papier
wiley   +1 more source

Plasma Tectonics and Electric Geology: Some Context on Geoplasma Research of Global Electric Circuits [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2020
Has anyone ever wondered why tornado outbreaks generally occur in the Spring, while hurricane season is in the Fall? The tilting of the Earth's North Pole towards the Sun in the Spring activates the northern global circuits connected to North America ...
Bruce Leybourne
doaj  

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