Results 71 to 80 of about 43,243 (288)

Fast Magnetic Twister and Plasma Perturbations in a 3-D Coronal Arcade

, 2014
We present results of 3-D numerical simulations of a fast magnetic twister excited above a foot-point of the potential solar coronal arcade that is embedded in the solar atmosphere with the initial VAL-IIIC temperature profile, which is smoothly extended
Murawski, K., Musielak, Z. E., Srivastava, A. K.   +2 more
core   +1 more source

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

British Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić, Ivana Stević, Elvira Meni Maria Gkrinia, Dinko Vitezić, Slobodan Janković   +4 more
wiley   +1 more source

A Review on Quantitative Process Analytical Technology for Continuous Downstream Processing of Monoclonal Antibodies

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The competition in the biopharmaceutical market is increasing due to the market entry of biosimilars and rising costs in research and development of new drugs. Hence, continuous manufacturing gained significant attention due to its potential in reducing production cycle times and costs, as well as the possibility of real‐time release testing ...
Mariana Carvalho, Ana Cruz, Cees Haringa, Marcel Ottens, Marieke Klijn   +4 more
wiley   +1 more source

Development of Raman Spectroscopy and Machine Learning Methods for Protein Aggregate Quantification: Application to BSA in Chromatographic Processes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Protein aggregation poses a significant risk to biopharmaceutical product quality, as even minor amounts of oligomeric species can compromise efficacy and safety. Rapid and reliable detection of protein aggregates thus remains a major challenge in biopharmaceutical manufacturing.
Jakob Heyer‐Müller, Robin Schiemer, Lars Robbel, Michael Schmitt, Jürgen Hubbuch   +4 more
wiley   +1 more source

Climate Change Risks and Customer Concentration: Evidence From US‐Listed Firms

Business Strategy and the Environment, EarlyView.
ABSTRACT While prior studies have investigated climate risks in supply chains, customer ESG pressures, and shared climate exposure, this paper is, to the best of our knowledge, the first to provide direct empirical evidence on the relationship between climate change risks and firms' customer concentration.
Thi Thuy Trang Nguyen, Eric Owusu Boahen, Cuong Nguyen   +2 more
wiley   +1 more source

Quality‐adjusted life years in the presence and absence of organized mammographic screening using data from BreastScreen Norway

International Journal of Cancer, EarlyView.
What's New? Although mammographic screening can reduce breast cancer mortality and extend life, some studies have found a negative impact on net quality‐adjusted life years (QALYs). Here, the authors estimated net QALYs associated with biennial mammographic screening for women aged 50–69 years in Norway under various scenarios.
Rick Groeneweg, Nicolien T. van Ravesteyn, Lindy M. Kregting, Giske Ursin, Solveig Hofvind, Nataliia Moshina   +5 more
wiley   +1 more source

Damage Analysis of Three Long-Track Tornadoes Using High-Resolution Satellite Imagery

Atmosphere, 2020
Remote sensing of tornado damage can provide valuable observations for post-event surveys and reconstructions. The tornadoes of 3 March 2019 in the southeastern United States are an ideal opportunity to relate high-resolution satellite imagery of damage ...
Daniel Burow, Hannah V. Herrero, Kelsey N. Ellis   +2 more
doaj   +1 more source

Understanding Autistic Young Adults' Perceptions and Experiences of Traumatic and Stressful Events

Journal of Clinical Psychology, Volume 81, Issue 6, Page 445-461, June 2025.
ABSTRACT Objectives The aim of this study was to explore how young autistic adults experience and respond to stressful life events, and the relationship between autistic characteristics and symptoms of stress associated with these events. Methods Using an exploratory sequential mixed‐methods approach, an online qualitative survey was first administered
Alliyza Lim, Robyn L. Young
wiley   +1 more source

Twisting/Swirling Motions During a Prominence Eruption as seen from SDO/AIA

, 2018
A quiescent prominence was observed at north-west limb of the Sun using different channels of Atmospheric Imaging Assembly (AIA) onboard Solar Dynamics Observatory (SDO).
Banerjee, D., Chandrashekhar, K., Datta, A., Pant, V., Ray, S.   +4 more
core   +1 more source

Weathering the storms of climate change: Preparing persons with disabilities and the physiatrists who provide their care for extreme hurricanes

PM&R, EarlyView.
Abstract Climate‐driven disasters have disproportionate and often devastating consequences on individuals with disabilities. Warming ocean and air temperatures are fueling more extreme tropical cyclones, further endangering those living in at‐risk regions.
Mollie Andreae, James M. Shultz, J. Marshall Shepherd, Zelde Espinel, Lauren T. Shapiro   +4 more
wiley   +1 more source