Results 41 to 50 of about 220,177 (308)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Are joint torque models limited by an assumption of monoarticularity? [PDF]

open access: yes, 2012
This study determines whether maximal voluntary ankle plantar flexor torque could be more accurately represented using a torque generator that is a function of both knee and ankle kinematics.
Yeadon, MR   +3 more
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Investigating Impact of Gasket Cylinder Addition and Octane Rating on Engine Performance

open access: yesQuantum Teknika
The increase in people's mobility were reflected in the growing sales of motor vehicles. This has driven automotive manufacturers to compete in creating more powerful and efficient engines.
Bahtiar Rahmat   +4 more
doaj   +1 more source

Project calculation of the steering mechanism hydraulic servo control in motor vehicles

open access: yesVojnotehnički Glasnik, 2013
Hydraulic servo controls are designed to facilitate rotation in place without providing increased ppower to steering wheels. In the initial design phase, the dimensions required for control systems are usually obtained through the calculation of their ...
Zoran Đukan Majkić
doaj   +1 more source

Forces Perspective of Drillability of Titanium Alloy 6Al-2Sn-4Zr-6Mo [PDF]

open access: yesJEMMME (Journal of Energy, Mechanical, Material, and Manufacturing Engineering), 2018
This paper concerns on drillability of Ti-6Al-2Sn-4Zr-6Mo (Ti-6246) from the point view of thrust force (Fz) & torque (Mz) using a TiAlN CVD coated carbide tool. The condition of the material was varied with three different heat treatments.
Mahros Darsin, Tim Pasang, Zhan Chen
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Physicochemical and sensory characterization of an extruded product from blue maize meal and orange bagasse using the response surface methodology

open access: yesCyTA - Journal of Food, 2018
The mixtures of blue cornmeal and orange bagasse were processed in a single screw laboratory extruder. We used an experimental design, central composite rotatable, where the factors were as follows: extruder die temperature (153–187°C), feed moisture ...
Ricardo O. Navarro-Cortez   +6 more
doaj   +1 more source

Optimization Performance Indices of Diesterol Fuel in Diesel Engine by Response Surface Methodology [PDF]

open access: yesJournal of Agricultural Machinery, 2018
Introduction Diesterol is a new specific term which denotes a mixture of fossil diesel fuel (D), vegetable oil methyl ester called biodiesel (B) and plant derived ethanol (E).
G Khoobbakht
doaj   +1 more source

Torque prediction using the flux-MMF diagram in AC, DC, and reluctance motors [PDF]

open access: yes, 1996
This paper uses the flux-MMF diagram to compare and contrast the torque production mechanism in seven common types of electric motor. The flux-MMF diagram is a generalized version of the flux-linkage versus current (ψ-i) diagram for switched-reluctance ...
Deodhar, R.P.   +3 more
core   +1 more source

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