Results 11 to 20 of about 11,585 (220)

Risperidone alone did not induce torsade de pointes: Experimental evidence from the chronic atrioventricular block model dogs

Journal of Pharmacological Sciences, 2020
We assessed torsadogenic action of risperidone, which can potently inhibit IKr as well as α1-adrenoceptor. A toxic dose of 3 mg/kg of risperidone was intravenously administered over 10 min to chronic atrioventricular block dogs without anesthesia with ...
Yoshio Nunoi, Koki Chiba, Mihoko Hagiwara-Nagasawa, Ai Goto, Ryuichi Kambayashi, Hiroko Izumi-Nakaseko, Yoshinori Takei, Akio Matsumoto, Yoshinori Watanabe, Atsushi Sugiyama   +9 more
doaj   +1 more source

Arrhythmic storm: Short-coupled variant torsade de pointes

Revista Portuguesa de Cardiologia, 2016
A 49-year-old woman, with no relevant family history, was admitted in 1996 for arrhythmic storm with polymorphic ventricular tachycardia (torsade de pointes) which degenerated into ventricular fibrillation.
Ana Rita Godinho, Cecília Frutuoso, Mariana Vasconcelos, Paula Dias, Raquel Garcia, Teresa Pinho, Vítor Araújo, Maria Júlia Maciel   +7 more
doaj   +1 more source

Tormenta eléctrica y torsade de pointes asociados a tratamiento con antimoniales en un paciente con leishmaniasis cutánea

Revista Colombiana de Cardiología, 2018
Resumen: La toxicidad por antimoniales puede comprometer múltiples sistemas y llega a ser potencialmente fatal. Se presenta el caso de un joven militar quien durante el tratamiento de su segundo episodio de leishmaniasis cutánea presentó toxicidad ...
Laura Arcos, Carlos Rincón, Diego Vanegas, Ramón Medina   +3 more
doaj   +1 more source

Comprehensive translational assessment of human-induced pluripotent stem cell derived cardiomyocytes for evaluating drug-induced arrhythmias [PDF]

, 2016
Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM) hold promise for assessment of drug-induced arrhythmias and are being considered for use under the comprehensive in vitro proarrhythmia assay (CiPA).
Blinova, Ksenia, Brock, Mathew, Chan, Dulciana, Chvatal, Stacie, Crumb, William J., Galeotti, Loriano, Hortigon-Vinagre, Maria P., Johannesen, Lars, Lyn-Cook, Beverly, Millard, Daniel, Pang, Li, Ross, James, Smith, Godfrey, Stockbridge, Norman, Stohlman, Jayna, Strauss, David G., Vicente, Jose, Zamora Rodriguez, Victor   +17 more
core   +1 more source

Pharmacological β-adrenoceptor blockade can augment torsadogenic action of IKr inhibitor: Comparison of proarrhythmic effects of d-sotalol and dl-sotalol in the chronic atrioventricular block dogs

Journal of Pharmacological Sciences, 2019
Information is still limited whether β-blockade may augment or attenuate the onset of torsade de pointes in patients with IKr inhibitor-induced labile repolarization process.
Ai Goto, Mihoko Hagiwara-Nagasawa, Koki Chiba, Ryuichi Kambayashi, Yoshio Nunoi, Hiroko Izumi-Nakaseko, Akio Matsumoto, Yasunari Kanda, Atsushi Sugiyama   +8 more
doaj   +1 more source

Adverse reactions of amiodarone [PDF]

, 2019
Adverse drug reaction is defined by the World Health Organization as any response to a drug that is noxious and unintended and occurs at a dose normally used in man.
Calvosa, Leonardo, Ciacciarelli, Marco, Colunga Biancatelli, Ruben Ml, Congedo, Viviana, Iuliano, Luigi, Polidoro, Alessandro   +5 more
core   +1 more source

Torsade de Pointes Triggered by Early Ventricular Escape Beats in a Patient with Complete Atrioventricular Block

Case Reports in Cardiology, 2016
Torsade de pointes is an uncommon and malignant form of polymorphic ventricular tachycardia and associated with a prolonged QT interval, which may be congenital or acquired.
Erkan Yildirim, Baris Bugan, Suat Gormel, Uygar Cagdas Yuksel, Murat Celik, Yalcin Gokoglan, Serdar Firtina, Sinan Iscen, Emre Yalcinkaya, Ugur Kucuk, Hasan Kutsi Kabul   +10 more
doaj   +1 more source

A case of hypoglycemiainduced QT prolongation leading to torsade de pointes and a review of pathophysiological mechanisms

Clinics and Practice, 2017
Torsades de pointes is a life-threatening cardiac arrhythmia. Occurrence of this arrhythmia as a result of hypoglycemia has not been reported in the literature.
Faris Hannoodi, Hashim Alwash, Kushal Shah, Israa Ali, Sarwan Kumar, Khalid Zakaria   +5 more
doaj   +1 more source

Polymorphic Ventricular Tachycardia Associated with High-Dose Methadone Use

Case Reports in Cardiology, 2020
Methadone is a well-tolerated drug that has been used for pain control and the treatment of opioid addiction. However, some fatal cardiac side effects have been reported previously, including ventricular arrhythmia, stress cardiomyopathy, and coronary ...
Weng-Chio Tam, U-Po Lam, Toi-Meng Mok, Tou Chang, Wa Ho, Mario Alberto De Brito Lima Evora   +5 more
doaj   +1 more source

Torsade de Pointes Following Myocarditis; A Case Report

Sakarya Tıp Dergisi, 2019
Myocarditis is defined as myocardial edema associated with non-ischemic necrosis in myocardial tissue. Acute viral myocarditis may cause several electrocardiographic changes. These include conduction disturbances, disorders of repolarization, ventricular
Kayıhan Karaman, Arif Arısoy, Samet Yılmaz   +2 more
doaj   +1 more source