Results 51 to 60 of about 8,444 (159)

Hormone Therapy Usage Is Associated With Adverse Cardiovascular Events in Prostate Cancer Patients of the All of Us Research Program Cohort

The Prostate, Volume 85, Issue 12, Page 1077-1086, September 2025.
ABSTRACT Background Hormone therapy (HT) has greatly improved overall survival for prostate cancer patients, but may also influence cardiovascular health in an already high‐risk population. Methods This retrospective cohort study examined participants in the All of Us Research Program with prostate cancer, had no prior history of adverse cardiovascular
Yuanchu J. Yang, Chenjie Zeng, Kerry R. Schaffer, Tam C. Tran, Peter J. Sauer, Lincoln A. Brown, Ben H. Park, Joshua C. Denny   +7 more
wiley   +1 more source

Prolactin Inhibition to Treat Postpartum Arrhythmic Storm

JACC: Case Reports
Postpartum electrical storm due to torsade de pointes is a rare but life-threatening condition. The uniqueness of this case lies in the use of cabergoline to suppress postpartum ventricular arrhythmias in absence of heart disease.
Miriam Compagnone, MD, Alessandro Marinelli, MD, Gianni Dall'Ara, MD, PhD, Matteo Ziacchi, MD, PhD, Simone Grotti, MD, Leonardo Ciurlanti, MD, Fabio Felice Tarantino, MD, Luciano Potena, MD, Mauro Biffi, MD, Marcello Galvani, MD   +9 more
doaj   +1 more source

Hydroxyzine, a First Generation H1-Receptor Antagonist, Inhibits Human Ether-a-go-go–Related Gene (HERG) Current and Causes Syncope in a Patient With the HERG Mutation

Journal of Pharmacological Sciences, 2008
QT prolongation, a risk factor for arrhythmias, can result from genetic variants in one (or more) of the genes governing cardiac repolarization as well as intake of drugs known to affect a cardiac K+ channel encoded by human ether-a-go-go–related gene ...
Tomoko Sakaguchi, Hideki Itoh, Wei-Guang Ding, Keiko Tsuji, Iori Nagaoka, Yuko Oka, Takashi Ashihara, Makoto Ito, Yoshihiro Yumoto, Naoko Zenda, Yukei Higashi, Youichi Takeyama, Hiroshi Matsuura, Minoru Horie   +13 more
doaj   +1 more source

Sacubitril Does Not Exert Proarrhythmic Effects in Combination with Different Antiarrhythmic Drugs

Pharmaceuticals
Background: Previous studies suggest a direct effect of sacubitril on cardiac electrophysiology and indicate potential arrhythmic interactions between sacubitril and antiarrhythmic drugs.
Christian Ellermann, Carlo Mengel, Julian Wolfes, Felix K. Wegner, Benjamin Rath, Julia Köbe, Lars Eckardt, Gerrit Frommeyer   +7 more
doaj   +1 more source

A Case of QT Prolongation Associated with Panhypopituitarism

Case Reports in Endocrinology, 2013
We describe a 37-year-old patient with panhypopituitarism who experienced symptoms and signs of hormonal insufficiency and QT prolongation on electrocardiogram without electrolyte disturbances.
Dilek Arpaci, Mustafa Volkan Demir, Tayfun Garip, Ali Tamer   +3 more
doaj   +1 more source

Cisapride-Induced Transmural Dispersion of Repolarization and Torsade de Pointes in the Canine Left Ventricular Wedge Preparation During Epicardial Stimulation [PDF]

, 2003
José M. Di Diego, Luiz Belardinelli, Charles Antzelevitch   +2 more
openalex   +1 more source

Idiopathic Intractable Diarrhoea Leading to Torsade de Pointes

Case Reports in Cardiology, 2016
An 81-year-old lady was admitted to our hospital with a 3-year history of noninfective diarrhoea and recurrent syncopal events over the last 3 months. Her initial electrocardiogram (ECG) revealed trigeminy and prolonged QTc interval.
Kyriacos Mouyis, Darlington Okonko, Constantinos G. Missouris   +2 more
doaj   +1 more source

Characterization of electropharmacological profile of an anti-atrial fibrillatory drug vernakalant along with potential risk toward torsade de pointes: Translational studies using isoflurane-anesthetized dogs and isolated rat aortic preparations

, 2023
Ai Goto, Ryuichi Kambayashi, Hiroko Izumi‐Nakaseko, Makoto Shinozaki, Yoshinori Takei, Atsushi Sugiyama   +5 more
openalex   +1 more source

Nearly Fatal Torsade de Pointes with Sotalol

Indian Pacing and Electrophysiology Journal, 2003
A 75-year-old woman with paroxysmal atrial fibrillation (AF) experienced recurrent seizures at home. Holter monitoring (each line 50 sec) showed repetitive runs of torsade de pointes (TdP), degenerating into ventricular fibrillation and ventricular ...
Bernhard Strohmer, Christiana Schernthaner, Maximilian Pichler   +2 more
doaj  

Possibility as an anti-cancer drug of astemizole: Evaluation of arrhythmogenicity by the chronic atrioventricular block canine model

Journal of Pharmacological Sciences, 2016
Since astemizole in an oral dose of 50 mg/kg/day was recently reported to exert anti-cancer effect in mice, we evaluated its proarrhythmic potential using the atrioventricular block dogs in order to clarify its cardiac safety profile.
Hiroko Izumi-Nakaseko, Yuji Nakamura, Xin Cao, Takeshi Wada, Kentaro Ando, Atsushi Sugiyama   +5 more
doaj   +1 more source