Results 71 to 80 of about 480,913 (287)
Genotype-Phenotype Relationships in Long QT Syndrome : Role of Mental Stress, Adrenergic Activity and a Common KCNH2 Polymorphism [PDF]
, 2006 Long QT syndrome is a congenital or acquired arrhythmic disorder which manifests as a prolonged QT-interval on the electrocardiogram and as a tendency to develop ventricular arrhythmias which can lead to sudden death.
Paavonen, Kristian
core
Clinical Pharmacology in Drug Development, Volume 15, Issue 1, January 2026.Abstract Milvexian is an oral factor XIa inhibitor in development for prevention of major thromboembolic conditions. This randomized, double‐blind, placebo‐ and positive‐controlled, multiple‐dose, four‐period crossover study assessed the cardic safety of milvexian (including effects on the QT interval of the electrocardiogram), with a supporting in ...
Peter Zannikos +10 more
wiley +1 more source
Rabbit models of heart disease. [PDF]
, 2008 Human heart disease is a major cause of death and disability. A variety of animal models of cardiac disease have been developed to better understand the etiology, cellular and molecular mechanisms of cardiac dysfunction and novel therapeutic strategies ...
Bers, Donald M, Pogwizd, Steven M
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Mapping and Ablating Ventricular Premature Contractions That Trigger Ventricular Fibrillation: Trigger Elimination and Substrate Modification [PDF]
, 2014 Ventricular fibrillation (VF) is a malignant arrhythmia, usually initiated by a ventricular premature contraction (VPC) during the vulnerable period of cardiac repolarization. Ablation therapy for VF has been described and increasingly reported.
NOGAMI AKIHIKO, 野上 昭彦
core +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 241-254, January 2026.Overview of the implemented pharmacogenomics (PGx) process in clinical routine at the Robert Bosch Hospital: from patient enrollment via the hospital information system, DNA detection using a customized TaqMan OpenArray panel and qPCR for CNV assessment, to clinical translation of genotyping results into PGx guideline‐based recommendations using a ...
Roman Tremmel +13 more
wiley +1 more source
Solifenacin linked QT interval prolongation and torsades de pointes [PDF]
, 2017 [no ...
Bray, Jonathan, Hancox, Jules
core +2 more sources
Acquired Long QT Syndrome and Torsades de Pointes after Mitral Valve Replacement Surgery
Journal of Cardiac Arrhythmias, 2021 Acquired long QT syndrome (aLQTS) can occur in up to one third of patients undergoing cardiac surgery and is often undisclosed. We present a case of a 55-year-old male patient admitted to our center for mitral valve replacement surgery, and, during the ...
Carlos Rodríguez-Artuza +4 more
doaj +4 more sources
Torsade de Pointes and Persistent QTc Prolongation after Intravenous Amiodarone
Case Reports in Medicine, 2012 We report a case of torsade de pointes after intravenous amiodarone and concurrent hypokalemia. Despite treatment cessation and correction of electrolyte abnormalities, excessive QTc prolongation was noted, which persisted for 14 days.
Anna P. Kotsia +3 more
doaj +1 more source
A Rare Case of Thiamine Deficiency Leading to Dry Beriberi, Peripheral Neuropathy, and Torsades De Pointes [PDF]
, 2023 Trevor Phinney +5 more
openalex +1 more source
Sildenafil helps the beat go on
Experimental Physiology, EarlyView.
Jules C. Hancox
wiley +1 more source