Results 21 to 30 of about 144,442 (285)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Introducción a la artillería de torsión

open access: yesGladius, 2011
La artillería de torsión grecorromana es un campo tan apasionante como poco estudiado en la bibliografía española. Del siglo IV a.C. al VI d.C., la evolución de este tipo de armamento —diseñado para lanzar dardos o piedras— está jalonada de hallazgos ...
Aitor Iriarte Kortazar
doaj   +1 more source

Estudio del efecto de la silice coloidal sobre la resistencia de un hilado. [PDF]

open access: yes, 1963
Se determina la resistencia que corresponde a ambos hilados bajo distintos estados de torsión, con el fin de establecer hasta qué punto la influencia de la sílice coloidal es de importancia bajo un punto de vista industrial en el caso que aquí ...
Victori Companys, Joan
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Adnexal torsion: is there a familial tendency?

open access: yesClinical and Experimental Obstetrics & Gynecology, 2020
Objective: To investigate whether patients diagnosed with adnexal torsion report a family history of adnexal torsion in a first degree relative. Materials and Methods: All women with a surgical diagnosis of adnexal torsion operated from 2008 to 2016 were
N. Smorgick   +5 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

La Influencia de Élie Cartan sobre la obra de Albert Einstein [PDF]

open access: yes, 2014
Sin Élie Cartan, las matemáticas y la física del siglo XX serían muy distintas de las que conocemos, especialmente en relación con el intento de Einstein de construir una teoría de campo unificado. Cartan introdujo la noción de "tétrada’" o vielbein, que
Alemañ, Rafael Andrés
core   +1 more source

Multimodal Mechanical Testing of Additively Manufactured Ti6Al4V Lattice Structures: Compression, Bending, and Fatigue

open access: yesAdvanced Engineering Materials, EarlyView.
In this experimental study, the mechanical properties of additively manufactured Ti‐6Al‐4V lattice structures of different geometries are characterized using compression, four point bending and fatigue testing. While TPMS designs show superior fatigue resistance, SplitP and Honeycomb lattice structures combine high stiffness and strength. The resulting
Klaus Burkart   +3 more
wiley   +1 more source

EBSD Study of Creep‐Induced Lattice Misorientation in MgO‐Particle‐Reinforced Austenitic Steel Composites

open access: yesAdvanced Engineering Materials, EarlyView.
Creep experiments at 900°C on coarse‐grained steel‐ceramic composites containing recycled magnesia reveal that higher ceramic volume fractions significantly enhance the creep resistance. Detailed EBSD investigations identify subgrain formation in the steel matrix as the dominant deformation mechanism.
Moritz Müller   +6 more
wiley   +1 more source

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