Results 111 to 120 of about 9,817 (309)

Investigating the Role of Type I Interferon Signaling on Muscle Disease Using Mouse Models

Arthritis &Rheumatology, EarlyView.
Objective Dysregulated type I interferon (IFN) signaling contributes to autoimmune myositis pathogenesis. We investigated the therapeutic effects of JAK inhibitors in two mouse models. We also examined how type I IFNs affect muscle vasculature. Methods Myositis was induced in major histocompatibility complex class I double transgenic ([TRE‐H‐2Kb (H ...
Rita Spathis, Sabrina Narvesen, Deeva Robles Kuriplach, Karen Huang, Teja Sundar, Elizabeth Bagley, Joanna Parkes, Xinyu Jia, Nandhana Sudhan, Alfredo Guzman, Kanneboyina Nagaraju, Melissa Morales   +11 more
wiley   +1 more source

Technique for Lateral Opening Wedge Distal Femoral Osteotomy Using Patient‐Specific Instrumentation for Genu Valgum and Patellar Instability

Arthroscopy Techniques, EarlyView.
Abstract Recurrent lateral patellar instability poses a technical challenge to orthopaedic surgeons. Isolated soft‐tissue procedures through medial patellofemoral ligament reconstruction or lateral release show unacceptably high failure rates. Lateral opening wedge distal femoral osteotomy addresses underlying bony malalignment and reinforces the soft ...
Alexander P. Decilveo, Elan Karlin, Neil Patel, Allison Ariniello, George F. Rick Hatch   +4 more
wiley   +1 more source

Asymmetric Central Processing of Sensory Stimuli in Idiopathic Focal Dystonia

Behavioural Neurology, 1997
Idiopathic torsion dystonia is characterized by persistent abnormalities of posture. We tested the hypothesis that abnormal sensorimotor processing is involved pathophysioiogically by looking for asymmetry of sensory processing in patients with ...
R. A. Grünewald, J. Shipman, Y. Yoneda, H. J. Sagar   +3 more
doaj   +1 more source

Drug‐coated balloons: From conventional designs to next‐generation innovations in vascular therapy

BMEMat, EarlyView.
This review traces the evolution of drug‐coated balloons (DCBs) from conventional designs to next‐generation platforms. We highlight innovations in balloon engineering, coating technologies, and therapeutic agents that enhance localized drug delivery while addressing challenges in efficiency, safety, and biocompatibility for vascular and emerging non ...
Lu Zhang, Jiawei Cui, Jin Wang, Manfred F. Maitz, Rifang Luo, Yunbing Wang   +5 more
wiley   +1 more source

Role of traditional Chinese medicine-based acupuncture in the resolution of ovarian torsion

Journal of Integrative Medicine and Research
Ovarian torsion (OT) is a gynecological emergency that affects females of childbearing age and usually requires surgical management. Here, we present a 30-year-old female who presented with an ultrasonographically confirmed OT along with an ovarian cyst ...
R. Shubha, Karishma Silwal, Pradeep M. K. Nair   +2 more
doaj   +1 more source

Physeal Growth Plate Fractures: Implications for the Pediatric Athlete [PDF]

, 2013
Pediatric musculoskeletal trauma accounts for most childhood injuries. The anatomy and physiology of the pediatric skeleton is unique as is its response to trauma.
Clark, Tara J., Cleary, Michelle A., Eberman, Lindsey E.   +2 more
core  

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Maximizing Neurovascular Outcomes of Facial Transplantation: A Comprehensive Review

Clinical Anatomy, EarlyView.
ABSTRACT Facial transplantation is a division of reconstructive surgery which aims to improve the function and appearance of a face that has endured severe disfigurement. Currently, the face transplant procedure uses allogenic tissue, harvested from a brain‐dead donor, to replace damaged facial components.
Olivia A. James, Faye Bennett
wiley   +1 more source

Magnitude of the Inglewood, California, earthquake of June 21, 1920 [PDF]

, 1970
Comparison with later earthquakes in the same area indicates a magnitude near 4.9 for the Inglewood, California, earthquake of June 21 ...
Richter, C. F.
core  

Clinical and Physiological Predictors of Acetylcholine‐Induced Coronary Spasm in ANOCA/INOCA Patients: A Retrospective Cohort Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background A substantial proportion of patients with angina and/or ischemia are found to have non‐obstructive coronary arteries (ANOCA/INOCA). Their symptoms can sometimes be explained by coronary microvascular dysfunction and/or vasospasm. Selecting patients for acetylcholine testing remains challenging, and the procedure is not trivial in ...
Jeremie Buri, Aurelia Zimmerli, Thabo Mahendiran, Adil Salihu, Victor Weerts, Olivier Muller, David Meier, Stephane Fournier   +7 more
wiley   +1 more source