Results 131 to 140 of about 5,713 (212)

Small‐Scale Magnetic Soft Robots for Medical Applications: From Laboratory to Clinical Use

open access: yesSmartBot, EarlyView.
Small‐scale magnetic soft robots are emerging as promising platforms for minimally invasive diagnosis and therapy in complex in vivo environments. This review compares untethered and tethered medical magnetic robots in parallel across five translational stages, from basic performance testing to clinical evaluation.
Xingxing Ke   +29 more
wiley   +1 more source

Impacts of Fluorination at the Ortho‐Position of Carboxy Groups on Tetrakis(biphenyl)ethene‐Based Hydrogen‐Bonded Framework

open access: yesSmall, EarlyView.
This work provides new findings on the effect of fluorination on the substitution of TPE derivatives and the modulation of the structure and fluorescence properties of hydrogen‐bonded organic framework (HOF) of F‐CBPE. ABSTRACT Fluorination of building block molecules is one of the effective engineering approaches to modulate molecular assembly in ...
Takuto Fujii   +8 more
wiley   +1 more source

Elective Robotic Splenectomy for Wandering Spleen-Associated Pancreatitis: A Novel Case Report. [PDF]

open access: yesClin Case Rep
Elshabrawi MN   +5 more
europepmc   +1 more source

Driving Drugs Deeper: Force‐Driven Microneedle Systems for Active Therapy and Their Road Towards Clinical Implementation

open access: yesSmall, EarlyView.
Force‐driven microneedles are presented as active therapeutic microdevices that overcome the diffusion limits of conventional patches. By integrating gas generation, magnetic actuation, cavitation, or iontophoresis, these systems drive payloads deeper into tissue, enabling faster, more controlled delivery and highlighting key design principles and ...
Majed Amini   +3 more
wiley   +1 more source

A lysosome‐targeted ultra‐sensitive viscosity probe for monitoring viscosity alterations during chemotherapy

open access: yesSmart Molecules, EarlyView.
A novel chemosensing platform based on a molecular rotor architecture is established for specific, dynamic detection of lysosomal viscosity. The platform allows real‐time tracking of lysosomal viscosity fluctuations induced by various chemotherapeutic agents, highlighting its significant potential as a powerful tool for early cancer diagnostics and ...
Haoyang Song   +6 more
wiley   +1 more source

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

open access: yesSmart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin   +10 more
wiley   +1 more source

A multifunctional near‐infrared dual‐channel off‐on‐off probe for sequential detection of fluoride and hypochlorous acid: Multimatrix applications

open access: yesSmart Molecules, EarlyView.
This multifunctional, sequence‐specific probe (DHM) enables stepwise detection: fluoride triggers red/near‐infrared emission via cleavage, then hypochlorous acid induces blue fluorescence. It achieves fast, selective visual detection in environmental samples, foods, and in vivo models.
Tongtong Li   +10 more
wiley   +1 more source

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