Results 151 to 160 of about 1,263,658 (344)

Association between glucocorticoid receptor beta and steroid resistance: A systematic review

open access: yesImmunity, Inflammation and Disease
Background Glucocorticoids are the most commonly used anti‐inflammatory drugs for a variety of diseases, despite the fact that resistance to them is growing in a number of conditions.
Md. Mojahidur Hasan, Sehreen Tory
doaj   +1 more source

Can Clarke square the circle of reforming criminal justice while also cutting costs by a quarter, by getting 20,000 people out of jail?. [PDF]

open access: yes
In a major speech that has already furrowed brows amongst the Tory right wing, Ken Clarke set out proposals for wide-ranging criminal justice reform. Simon Bastow listened to his speech and sets it against the overall picture of pressures on the Ministry
Bastow, Simon
core   +1 more source

Increased expression of aromatase after focal cerebral ischemia: Relevance to neuroprotection and functional recovery

open access: yesNeuroprotection, EarlyView.
Abstract Aim Aromatase is the key enzyme in the biosynthesis of 17β‐estradiol, the most potent estrogen, which has pleiotropic neuroprotective properties. Aromatase levels increase in the brain after stroke, and its gene variants increase susceptibility to stroke. This study aims to determine whether aromatase overexpression improves stroke outcome and
Lindsay Gallagher   +8 more
wiley   +1 more source

Efficacy and Safety of Dexmedetomidine‐Esketamine Versus Dexmedetomidine Alone as Premedication for Pediatric Anesthesia Induction: A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Background Emergence delirium (ED) is a common complication in pediatric anesthesia. Although intranasal dexmedetomidine (DEX) is widely used, its application is constrained by a slow onset, residual risk of ED in some patients, and risks such as bradycardia and hypotension.
Munder Lateiresh   +5 more
wiley   +1 more source

The relationship between Indigenous Peoples' lands and conservation: A systematic literature review

open access: yesPeople and Nature, EarlyView.
Abstract A growing body of peer‐reviewed literature is focused on the relationship between Indigenous Peoples' lands (Indigenous lands) and conservation outcomes. We performed a systematic review of this English reported peer‐reviewed literature (n = 111) to examine: the key characteristics; the conservation outcomes documented; the methods used in ...
William Nikolakis   +4 more
wiley   +1 more source

CARACTERÍSTICAS DEMOGRÁFICAS, HÁBITOS DE VIDA E HISTORIA DEL CONSUMO DE TABACO DE LOS FUMADORES OCASIONALES EN ESPAÑA

open access: yesRevista Española de Salud Pública, 2002
Back ground. This study des cribes the so cio de mo grap hic cha rac te ris tics, health-re lated li fest yle, and his tory of to bac co con sump tion of the oc casional smo kers in Spain, and exa mines whet her they show dif fe ren ces against daily ...
Lucía Díez Gañán   +5 more
doaj  

Gene List Selection Matters: Missed Diagnoses in Prenatal Exome Sequencing—PanelApp R21 and HPO‐Driven Versus OMIM‐Based Gene Lists

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective To evaluate whether the causative variants found upon clinical exome sequencing in fetuses affected with selected structural anomalies would also be detected if PanelApp‐R21 or Human Phenotype Ontology (HPO)‐driven gene selection terms were applied instead.
Victoria Ardiles‐Ruesjas   +7 more
wiley   +1 more source

The Clinical Utility of Sequence‐Based Genetic Testing for Fetal Edema Following Non‐Diagnostic Microarray Results: A Population‐Based Cohort Study

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective Ultrasound findings of fetal edema may provide early evidence of a genetic disorder. Our objective was to evaluate the frequency and diagnostic yield of sequencing in a selected population after a non‐diagnostic microarray result for fetal edema.
Victoria M. Allen   +5 more
wiley   +1 more source

Digitalising biodiversity: Exploring perceptions on risks and opportunities

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Digitalisation is transforming biodiversity conservation, offering new opportunities for research, governance and public engagement. Herbarium digitisation, for example, enables large‐scale access to plant data, supporting conservation, restoration and sustainable use.
Björn‐Ola Linnér   +9 more
wiley   +1 more source

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