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Results 171 to 180 of about 122,989 (258)

ALT phenotype assessment in IDH‐mutant astrocytoma supports biologic consequence of ATRX missense mutations

Brain Pathology, EarlyView.
A meaningful subset of IDH‐mutant astrocytoma harbors ATRX missense variants that retain ATRX IHC immunoreactivity yet exhibit functional ALT activation, supporting the biologic relevance of these missense mutations.
Oguzhan O. Kizilkaya +13 more
wiley +1 more source

Selective excitatory effects of γ‐glutamyl‐glycine, a glutathione metabolite, on GluN1 NMDA and mGlu5 receptors impacting synaptic plasticity

British Journal of Pharmacology, EarlyView.
Background and Purpose Gamma‐glutamyl dipeptides are essentially produced after glutathione (GSH) degradation. While several γ‐glutamyl dipeptides have been detected in different organs and body fluids, their biological activity remains elusive. This is the case for γ‐Glutamyl‐Glycine (γ‐Glu‐Gly) which has been found in different brain areas.
Sandro Andreu +20 more
wiley +1 more source

Toward Precision Reproductive Psychiatry: A Call for Targeted, Transdiagnostic Approaches to Premenstrual Disorders. [PDF]

Am J Psychiatry
Eisenlohr-Moul TA.
europepmc +1 more source

Economic Evaluation of the RETURN Intervention to Increase Routine Dental Attendance Among Disadvantaged Adults: Net Health Benefit (QALYs) and Patient Cost Outcomes From a Randomised Controlled Trial

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives Routine dental attendance is associated with better health outcomes, yet those from disadvantaged backgrounds are more likely to seek problem‐driven, episodic care. The RETURN intervention, a brief behavioural intervention delivered by dental nurses in urgent care, was designed to support urgent care users to take up planned dental ...
Tayamika Zabula +3 more
wiley +1 more source

Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study

Clinical &Experimental Allergy, Volume 55, Issue 3, Page 226-238, March 2025.
In a study assessing mobile health data, (i) adherence to rhinitis medication was highest for oral antihistamines and lowest for azelastine‐fluticasone, (ii) in weeks of partial adherence, azelastine‐fluticasone was associated with lower levels of reported rhinitis symptoms than other medication classes.
Bernardo Sousa‐Pinto +121 more
wiley +1 more source

Premium Intraocular Lens Selection in Patients With Glaucoma: A Clinical Review

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Glaucoma frequently coexists with cataract, but glaucomatous functional loss, ocular‐surface disease, anatomical abnormalities, and treatment‐related refractive variability may reduce tolerance of premium intraocular lenses. This narrative review critically appraises evidence relevant to lens selection in glaucoma. Central visual‐field status,
Zhihao Liu +3 more
wiley +1 more source

Serendipitous Explanations: Interaction‐Triggered Comprehension Aids in Visualization

Computer Graphics Forum, EarlyView.
Abstract Evidence continues to accrue around the difficulties people have understanding new and complex visualizations, which in turn provides continued incentive to explore additional methods of supporting visualization viewers. Through leveraging viewers' spontaneous visualization sensemaking activities, we introduce a Serendipitous Explanation ...
M. Rezaie, M. Tory, S. Carpendale
wiley +1 more source

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