Results 91 to 100 of about 9,173 (201)

ASPETTI REGOLATORI SULL'USO TERAPEUTICO DEI FARMACI: IL CASO DEL SOFOSBUVIR E DEL NIVOLUMAB [PDF]

open access: yes, 2015
The purpose of this Thesis is the discussion about regulatory aspects of "compassionate use" of drugs and in particular the relative Italian regulations and necessary procedures to apply them correctly (for example, important documents to be submitted to
CORVAGLIA, LOUIS GIUSEPPE
core  

How to master the host immune system? Leishmania parasites have the solutions! [PDF]

open access: yes, 2017
Infection by protozoan parasites of the genus Leishmania results in the development of leishmaniasis, an increasingly prevalent group of diseases affecting over 12 million people worldwide.
Fasel, N., Rossi, M.
core   +1 more source

Sensitivity and Precision of Search Strategies Built Using a Text‐Mining Word Frequency Tool (PubReMiner) Compared to Current Best Practice for Building Search Strategies: A Study Within a Review (SWAR)

open access: yesCochrane Evidence Synthesis and Methods, Volume 4, Issue 2, March 2026.
ABSTRACT Objective PubReMiner is a text‐mining tool that analyses a seed set of citations to assess word frequency in titles, abstracts, and Medical Subject Headings (MeSH). This study aimed to determine the sensitivity and precision of search strategies developed using the PubReMiner tool compared to conventional search strategies developed by a ...
Andrew Dullea   +10 more
wiley   +1 more source

The Burden of Acute Respiratory Infections on Emergency Departments: A Retrospective Study From a University Hospital in Central Italy

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Acute respiratory infections (ARIs) have a relevant impact on public health in terms of prevalence and costs associated with the diseases. While the COVID‐19 pandemic highlighted the need to adopt accurate surveillance systems to face new emergencies, the aim of our work is to describe ARIs other then COVID‐19 and their ...
Nunzio Zotti   +10 more
wiley   +1 more source

Ricerca di Rickettsia del gruppo "Spotted Fever" in zecche antropofile raccolte in Toscana e Liguria [PDF]

open access: yes, 2012
Several tick-borne rickettsiae cause human diseases and, in the last years, the increased use of molecular-based identification methods has resulted in new spotted fever group rickettsiae being characterized in ixodid ticks throughout Europe.
FICHI, GIANLUCA
core  

Seasonal and Environmental Influences on Free Sugar and Amino Acid Profiles of Lycium barbarum Berries Cultivated in Southern Tuscany

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
The graphical abstract illustrates how temperature, rainfall, and ripening stage shape the metabolic profile of Lycium barbarum berries grown in Southern Tuscany. It highlights the optimal harvest window (S2–S4) and summarizes key trends in sugars (glucose, fructose, pectins) and amino acids (total FAAs, proline, BABA, ornithine). Visual cues show that
Letizia Poggioni   +4 more
wiley   +1 more source

TTV Load Mirrors Local Immunity and Tracks HPV Positivity in the Anogenital Tract

open access: yesJournal of Medical Virology, Volume 98, Issue 2, February 2026.
ABSTRACT Torquetenovirus load has been proposed as an immunomodulated biomarker of host immune status, yet its behavior in situ within HPV‐infected mucosa remains poorly defined. We conducted a retrospective cross‐sectional study of 220 patients undergoing HPV screening (181 cervical swabs, 39 anal brushings). HPV was genotyped with Allplex™ HPV28, and
Lilia Cinti   +6 more
wiley   +1 more source

Insights Into Late‐Onset Rheumatoid Arthritis (LORA): Characteristics (Clinical and Imaging), Comorbidities, and Therapeutic Targets

open access: yesGeriatrics &Gerontology International, Volume 26, Issue 2, February 2026.
The main features of late‐onset rheumatoid arthritis (LORA), manifesting after age 65, are acute onset, higher disease activity, systemic involvement, and less presence of autoantibodies. Management requires individualized strategies, balancing aggressive treat‐to‐target therapy in robust patients with frailty‐focused approaches to prevent geriatric ...
Fausto Salaffi   +6 more
wiley   +1 more source

Toscana virus infections: A case series from France

open access: yesJournal of Infection, 2014
Toscana virus (TOSV) is a neglected sandfly-borne pathogen in Mediterranean countries. Although discovered four decades ago, articles that describe the clinical aspects are scarce and consist mostly of case reports, with few series of cases. We studied retrospectively symptomatic TOSV infections in patients hospitalized in Marseille (France) from 2004 ...
Dupouey, J.   +6 more
openaire   +3 more sources

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