Results 221 to 230 of about 57,882 (282)

Pathomics Signature for Prognosis and CA19‐9 Interception in Pancreatic Ductal Adenocarcinoma: A Real‐Life, Multi‐Center Study

Advanced Science, EarlyView.
This study develops a deep learning‐based pathomics model to predict survival outcomes in pancreatic cancer patients. The CrossFormer architecture analyzes routine H&E‐stained tissue slides, identifying key prognostic features including stromal patterns, cellular characteristics, and immune infiltration.
Qiangda Chen, Zhihang Xu, Yiping Zou, Zhenlai Jiang, Yecheng Li, Taochen He, Hanlin Yin, Jiali Li, Yanfei An, Jiande Han, Yuqi Xie, Wei Gan, Yaolin Xu, Wenquan Wang, Junyi He, Haibo Wang, Wenchuan Wu, Zhenyu Ye, Wenhui Lou, Jihui Hao, Liang Liu, Jun Yu, Ning Pu   +22 more
wiley   +1 more source

Triple Cross-Locking Technique for Medial Meniscus Root Repair. [PDF]

Arthrosc Tech
Aghamalyan HH, Vetoshkin AA.
europepmc   +1 more source

Imperfection in Semiconductors Leading to High Performance Devices

Advanced Science, EarlyView.
Crystalline perfection is typically pursued in semiconductors to enhance device performance. However, through modeling and experimental work, we show that defects can be strategically employed in a specific detection regime to increase sensitivity to extreme values. GaN diodes are demonstrated to effectively detect high‐energy proton beams at fluxes as
Jean‐Yves Duboz, Matilde Siviero, Lucas Lesourd, Eric Frayssinet, Sebastien Chenot, Petter Hofverberg, Sullivan Marafico, Marie Vidal, Maxime Hugues   +8 more
wiley   +1 more source

Nanoconfined entanglement-enhanced phase separation enables tough and contractile ionogel fibers. [PDF]

Nat Commun
Xu Z, Xu T, Feng J, Guo P, Yao X, Qin H, Cong HP.   +6 more
europepmc   +1 more source

The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis

Advanced Science, EarlyView.
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo, Yalin Wang, Binyu Lu, Yu Zhang, David M. Frazer, Bing Zhou   +5 more
wiley   +1 more source

Sleep Disorders and Obesity in Saudi Populations Across the Lifespan: A Systematic Review. [PDF]

J Clin Med
Aljohani AH, Aljohani AH, Alshammari KM.
europepmc   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

Magnetic Flux Guides by Material Extrusion

Advanced Science, EarlyView.
Magnetic flux guidance can increase inductive coupling and forces for magnetic sensors, actuators, and transducers. Here, a magnetic material extrusion method is used to fabricate flux concentration structures of arbitrary shapes with a magnetic permeability of 42. In line with simulation analysis, experimental results show that these materials provide
Jorge Cañada, Steven W. Wright, Michail E. Kiziroglou, Eric M. Yeatman, Luis F. Velásquez‐García   +4 more
wiley   +1 more source

Associations of accelerometer-estimated sleep with cardiorespiratory fitness and energetic efficiency among middle-aged and older adults. [PDF]

J Gerontol A Biol Sci Med Sci
Callow DD, Yue Y, Diallo I, Rabinowitz JA, An Y, Alfini AJ, Wu MN, Wanigatunga SK, Wanigatunga AA, Ferrucci L, Simonsick EM, Schrack JA, Spira AP.   +12 more
europepmc   +1 more source

Dead Matter, Living Machines: Repurposing Crustaceans' Abdomen Exoskeleton for Bio‐Hybrid Robots

Advanced Science, EarlyView.
Crustacean exoskeletons, repurposed from food waste, are engineered into sustainable bending actuators combining biotic structure with synthetic control. The augmented exoskeletons achieve rapid and robust motion with lightweight body and can be used as part of robotic manipulators, grippers and swimmers.
Sareum Kim, Kieran Gilday, Josie Hughes
wiley   +1 more source