BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai +7 more
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The Prognostic Value of Preoperative Total Cholesterol in Surgically Treated Oral Cavity Cancer. [PDF]
Tsai YT +12 more
europepmc +1 more source
Predictive value of biochemical markers CRP, WBC, and total cholesterol for postoperative dry eye syndrome following phacoemulsification cataract surgery. [PDF]
Wang Y, Wang X, Li Z, Yang H, Zhang X.
europepmc +1 more source
Association of total cholesterol to high-density lipoprotein cholesterol ratio with diabetes risk: a retrospective study of Chinese individuals. [PDF]
Zhang Z +7 more
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Levothyroxine therapy reduces endocan and total cholesterol concentrations in patients with subclinical hypothyroidism. [PDF]
Serdar Hiršl T +7 more
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Association between elevated serum total cholesterol and increased risk of post-induction hypotension in elderly patients undergoing non-cardiac surgery: a retrospective cohort study. [PDF]
Yang Y, Gong C, Jiang H, Luo Z, Chen L.
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Independent association of weight-adjusted waist index with asthma in U.S. adolescents: Mediating roles of eosinophil percentage, total cholesterol, and HDL cholesterol. [PDF]
He L, Deng Y, Liu X, Wang Y, Tang J.
europepmc +1 more source
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Total cholesterol and mortality in the elderly
Journal of Internal Medicine, 2003Abstract Casiglia E, Mazza A, Tikhonoff V, Scarpa R, Schiavon L, Pessina AC (Department of Clinical and Experimental Medicine, University of Padova, Italy). Total cholesterol and mortality in the elderly. J Intern Med 2003; 254: 353–362.Objective. To evaluate, at a population level, whether total cholesterol (TC) is a risk factor of mortality.
CASIGLIA, EDOARDO +5 more
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Total cholesterol and suicidality in depression
Biological Psychiatry, 1994There exists considerable controversy regarding an association between low total cholesterol and increased mortality from suicide. As suicide mortality is a crude marker for suicidal ideation and behavior, we investigated the association between total cholesterol and suicidality in a depressed sample.
P F, Sullivan +4 more
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We describe the preparation of glutaraldehyde cross-linked and functionalized cholesterol esterase nanoparticles (ChENPs) and cholesterol oxidase nanoparticles (ChOxNPs) aggregates and their co-immobilization onto Au electrode for improved amperometric determination of serum total cholesterol. Transmission electron microscope (TEM) images of ChENPs and
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