ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Energy-driven K-means-based LEACH routing protocol for enhanced lifetime in wireless sensor networks. [PDF]
Saroit IA, Tarek D.
europepmc +1 more source
[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich +19 more
wiley +1 more source
Associations between exposure to intimate partner violence (IPV) and infant developmental delay: moderating role of women's empowerment at six weeks postpartum. [PDF]
Nisar A +7 more
europepmc +1 more source
Dementia Incidence in Individuals With Parkinson's Disease in the Framingham Heart Study
ABSTRACT Limited information exists on incident dementia in individuals with Parkinson's disease (PD) in US community‐based samples. We examined cognitive statuses and PD diagnoses of 183 individuals in the Framingham Heart Study (FHS) to establish incident dementia, mortality rates, associations with sex, age at PD onset, and education level.
Joshi Dookhy +11 more
wiley +1 more source
Studying Evolutionary Solution Adaption by Using a Flexibility Benchmark Based on a Metal Cutting Process. [PDF]
Dal Piccol Sotto LF +4 more
europepmc +1 more source
"You're still online…who are you talking to, love?": the Affective-Sexual Violence Scale in young couples. [PDF]
Cámara-Pastor T +3 more
europepmc +1 more source
Culture of paternalism in the emergency department: a critical ethnographic study. [PDF]
Davoudi N +4 more
europepmc +1 more source
Serotype Distribution of <i>Aggregatibacter actinomycetemcomitans</i> in Periodontitis Patients. [PDF]
Khzam N, Kujan O, Haubek D, Miranda LA.
europepmc +1 more source
Total Dominating Sets and Total Domination Polynomials of Square Of Wheels
openaire +1 more source

