Results 81 to 90 of about 13,115 (262)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Graphs whose vertex set can be partitioned into a total dominating set and an independent dominating set [PDF]
Opuscula MathematicaA graph \(G\) whose vertex set can be partitioned into a total dominating set and an independent dominating set is called a TI-graph. We give constructions that yield infinite families of graphs that are TI-graphs, as well as constructions that yield ...
Teresa W. Haynes, Michael A. Henning
doaj +1 more source
Total domination and total domination subdivision number of a graph and its complement
Discrete Mathematics, 2008 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Odile Favaron +2 more
openaire +2 more sources
Computing locating-total domination number in some rotationally symmetric graphs. [PDF]
Sci Prog, 2021 Raza H, Iqbal N, Khan H, Botmart T.
europepmc +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Augmenting graphs to partition their vertices into a total dominating set and an independent dominating set [PDF]
Opuscula MathematicaA graph \(G\) whose vertex set can be partitioned into a total dominating set and an independent dominating set is called a TI-graph. There exist infinite families of graphs that are not TI-graphs. We define the TI-augmentation number \(\operatorname{ti}(
Teresa W. Haynes, Michael A. Henning
doaj +1 more source
Secure domination and secure total domination in graphs
Discussiones Mathematicae Graph Theory, 2008 A secure (total) dominating set of a graph G = (V; E) is a (total) dominating set X V with the property that for each u 2 V X, there exists x 2 X adjacent to u such that (X fxg) [ fug is (total) dominating. The smallest cardinality of a secure (total) dominating set is the secure (total) domination number s(G) ( st(G)).
William Klostermeyer +1 more
openaire +1 more source