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Total domination subdivision numbers of graphs
Summary: A set \(S\) of vertices in a graph \(G=(V,E)\) is a total dominating set of \(G\) if every vertex of \(V\) is adjacent to a vertex in \(S\). The total domination number of \(G\) is the minimum cardinality of a total dominating set of \(G\). The total domination subdivision number of \(G\) is the minimum number of edges that must be subdivided (
Haynes, Teresa W. +2 more
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Quasi total double Roman domination in graphs
A quasi total double Roman dominating function (QTDRD-function) on a graph [Formula: see text] is a function [Formula: see text] having the property that (i) if f(v) = 0, then vertex v must have at least two neighbors assigned 2 under f or one neighbor w
S. Kosari +4 more
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Inequalities involving independence domination, f-domination, connected and total f-domination numbers [PDF]
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Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
On the total domatic number of regular graphs [PDF]
A set S of vertices of a graph G = (V;E) without isolated vertex is a total dominating set if every vertex of V (G) is adjacent to some vertex in S.
H. Aram +2 more
doaj
Total domination numbers of cartesian products
Let $G\Box H$ denote the cartesian product of graphs G and H. Here we determine the total domination numbers of $P_5\Box P_n$ and $P_6\Box P_n$.
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