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Total domination subdivision numbers of graphs

open access: yesDiscussiones Mathematicae Graph Theory, 2004
Summary: A set \(S\) of vertices in a graph \(G=(V,E)\) is a total dominating set of \(G\) if every vertex of \(V\) is adjacent to a vertex in \(S\). The total domination number of \(G\) is the minimum cardinality of a total dominating set of \(G\). The total domination subdivision number of \(G\) is the minimum number of edges that must be subdivided (
Haynes, Teresa W.   +2 more
openaire   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Quasi total double Roman domination in graphs

open access: yesAKCE International Journal of Graphs and Combinatorics
A quasi total double Roman dominating function (QTDRD-function) on a graph [Formula: see text] is a function [Formula: see text] having the property that (i) if f(v) = 0, then vertex v must have at least two neighbors assigned 2 under f or one neighbor w
S. Kosari   +4 more
doaj   +1 more source

Inequalities involving independence domination, f-domination, connected and total f-domination numbers [PDF]

open access: yesCzechoslovak Mathematical Journal, 2000
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

On the total domatic number of regular graphs [PDF]

open access: yesTransactions on Combinatorics, 2012
A set S of vertices of a graph G = (V;E) without isolated vertex is a total dominating set if every vertex of V (G) is adjacent to some vertex in S.
H. Aram   +2 more
doaj  

Total domination numbers of cartesian products

open access: yesMathematical communications, 2004
Let $G\Box H$ denote the cartesian product of graphs G and H. Here we determine the total domination numbers of $P_5\Box P_n$ and $P_6\Box P_n$.
openaire   +4 more sources

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