Results 71 to 80 of about 11,484 (286)

Bounds on the Locating-Total Domination Number in Trees

Discussiones Mathematicae Graph Theory, 2020
Given a graph G = (V, E) with no isolated vertex, a subset S of V is called a total dominating set of G if every vertex in V has a neighbor in S. A total dominating set S is called a locating-total dominating set if for each pair of distinct vertices u ...
Wang Kun, Ning Wenjie, Lu Mei
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Results on the domination number and the total domination number of Lucas cubes

Ars Mathematica Contemporanea, 2020
Summary: Lucas cubes are the special subgraphs of Fibonacci cubes. For small dimensions, their domination numbers are obtained by direct search or integer linear programming. For larger dimensions some bounds on these numbers are given. In this work, we present the exact values of total domination number of small dimensional Lucas cubes and present ...
openaire   +2 more sources

Total domination subdivision numbers of trees

Discrete Mathematics, 2004
The total domination subdivision number \(\text{ sd}_{\gamma_t}(G)\) of a graph \(G\) is the minimum number of edges whose subdivision increases the total domination number \({\gamma_t}(G)\) of \(G\). \textit{T. W. Haynes} et al. [J. Comb. Math. Comb. Comput.
Haynes, Teresa W., Henning, Michael A., Hopkins, Lora   +2 more
openaire   +3 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Maker-Breaker total domination number

The Maker-Breaker total domination number, $γ_{\rm MBT}(G)$, of a graph $G$ is introduced as the minimum number of moves of Dominator to win the Maker-Breaker total domination game, provided that he has a winning strategy and is the first to play. The Staller-start Maker-Breaker total domination number, $γ_{\rm MBT}'(G)$, is defined analogously for the
Divakaran, Athira, James, Tijo, Klavžar, Sandi, Nair, Latha S   +3 more
openaire   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Bounds on the 2-domination number in cactus graphs [PDF]

Opuscula Mathematica, 2006
A \(2\)-dominating set of a graph \(G\) is a set \(D\) of vertices of \(G\) such that every vertex not in \(S\) is dominated at least twice. The minimum cardinality of a \(2\)-dominating set of \(G\) is the \(2\)-domination number \(\gamma_{2}(G)\).
Mustapha Chellali
doaj