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EFFECT OF ORPHENADRINE ON TOTAL THYROXINE
Acta Medica Scandinavica, 1974Abstract. Three clinically euthyroid patients with parkinsonism were found to have raised levels of protein‐bound thyroxine (T4(D)). It was demonstrated that treatment with orphenadrine (Disipal®) caused an elevation of T4(D) up to more than 100%. The increase was dose‐dependent and the underlying mechanism remained unknown.
B, Beermann, P O, Wester
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