Results 261 to 270 of about 29,262,902 (336)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Registration and reporting characteristics of trials investigating exercise therapy following total knee arthroplasty: a systematic review. [PDF]

Acta Orthop
Grønfeldt BM, Husted RS, Brødsgaard RH, Holst L, Kallemose T, Chapple CM, Juhl CB, Bandholm T.   +7 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Short-term effects of bone meal powder on soil phosphorus availability, seed germination, and early growth parameters of Malabar Spinach (Basella alba). [PDF]

PLoS One
Roy A, Sarker P.
europepmc   +1 more source

Effect of ERAS-based refined nursing on postoperative pain management in lung cancer surgery patients. [PDF]

Front Surg
Zhang J, Wang B, Li X, Qi F, Wang Y.
europepmc   +1 more source

The Orexin System Modulates Stress-Induced Alcohol Preference and Reinstatement in Adolescents: Bioinformatics and Experimental Evidence. [PDF]

Addict Biol
He W, Hu A, Zhao T, Deng L, Wu H, Xiang X.   +5 more
europepmc   +1 more source

Ultrasound-Guided Erector Spinae Plane Block Versus Transversus Abdominis Plane Block for Postoperative Analgesia in Adult Patients Undergoing Laparoscopic Appendectomy. [PDF]

Anesthesiol Res Pract
Mohamed Soliman EA, Abdelgani Basyoni M, Hafni Soliman AF, Abdelmawla Saleh M, Attia Sami ES.   +4 more
europepmc   +1 more source

Recurrence risk of differentiated thyroid cancer treated with total or hemithyroidectomy: systematic review and meta-analysis. [PDF]

Eur Thyroid J
Piccardo A, Fiz F, Bottoni G, Treglia G, Trimboli P.   +4 more
europepmc   +1 more source